摘要
目的 :研究胡麻油烟冷凝物对小鼠致突变作用。方法 :采用不同剂量胡麻油烟冷凝物灌胃染毒小鼠 ,通过微核实验和精子畸形分析 ,观察微核率和精子畸形率变化。结果 :各染毒组微核率和精子畸形率均明显高于阴性对照组和胡麻油对照组 (P <0 0 1) ,并呈现剂量反应关系 (P <0 0 5 )。结论 :在上述两实验系统中 ,胡麻油烟冷凝物具有明显的致突变作用。
Objective:To observe mutagenicity of siritch vapor condensate(SVC)in mice.Methods:The rates of micronucleus and sperm deformity in mice were observed with the micronucleus test (MNT) and sperm deformity analysis (SDA) respectively.Results:The rate of micronucleus and sperm deformity in SVC-treated groups was significantly higher than that of control group (P<0.01).Conclusion:Mutagenicity of SVC on the micronucleus formation and sperm deformity exists affirmatively in mice.
出处
《宁夏医学院学报》
2001年第1期1-2,共2页
Journal of Ningxia Medical College
