摘要
目的高尿酸和高血红蛋白血症患者在高原地区发病率非常高,为了解高原地区高尿酸血症和高血红蛋白血症的相关性,以便为针对性的治疗高原地区大量高尿酸血症患者提供依据.方法对在昆明医科大学第一附属医院体检的500人进行性别、年龄、尿酸、外周血红细胞等因素进行相关性分析.结果患高尿酸血症者134人(26.8%),外周血红细胞异常患者90人(18.2%),高血红蛋白血症患者55人(11.1%),Spearman相关和Pearson相关分析结果尿酸与红细胞和血红蛋白呈正相关,相关系数具有统计学意义(P<0.01);单因素分析结果尿酸与红细胞和血红蛋白,差异具有统计学意义(P<0.01);线性回顾分析外周血红细胞与尿酸差异具有统计学意义(P<0.01),Logistic回归分析血红蛋白与尿酸差异具有统计学意义(P<0.01).结论高尿酸血症的发生与外周血红细胞和血红蛋白呈正相关.
Objective The incidence of hyperuricemia and hyperhemoglobinemia is very high in plateau area, to understand the correlation between hyperalricemia and hyperhemoglobinemia plateau area, so as to provide the basis for the plateau region targeted therapy of patients with hyperuricemia. Method We ananlyzed the correlation between the age, gender, uric acid and peripheral blood erythrocytes of 500 subjects who received physical examination in the first affiliated hospital of kunming medical university. Results There were 134 （26.8%） patients with hyperuricemia, 90 （18.2%） patients with abnormal peripheral blood erythrocytes, and 55 （11.1%） patients with hyperhemoglobinemia. Spearman correlation and Pearson correlation analysis results showed uric acid and red blood cells and hemoglobin were positively correlated and the correlation coefficient with statistical significance （P〈O.O1） Single factor analysis results showed uric acid and red blood ceils and hemoglobin had statistically significant difference （P〈O.O1） . Linear regression analysis results showed that peripheral blood erythrocyte and uric acid had statistically significant differences （P〈O.O1） . Logistic regression analysis showed that hemoglobin and uric acid had statistically significant differences （P〈O.O1） . Conclusion The occurrence of hyperuricemia is positively correlated with the peripheral blood erythrocyte and hemoglobin.
出处
《昆明医科大学学报》
CAS
2014年第4期83-86,共4页
Journal of Kunming Medical University
基金
云南省科技厅昆明医科大学联合专英基金资助项目(2012FB032)
