摘要
采用反相 ＨＰＬＣ法，以Ｃ１８为固定相，乙腈－１０ｍｍｏｌ／Ｌ醋酸铵缓冲液（ｐＨ ６．０）（６０： ４０）为流动相，检测波长为２２９ｎｍ，流速为１．０ｍｌ／ｍｉｎ，测定了盐酸吡格列酮片的含量。线性范围为１０～２００μｇ／ｍｌ，平均回收率为９９．７３％（ＲＳＤ＝１．２２％）。
An HPLC method was established to assay the content of pioglitazone hydrochloride tablets. The solid phase was Hypersil C18. The mobile phase consisted of acetonitrile and 10mmol/L ammonium acetate buffer(pH 6.0) (60: 40). The detector was set at 229nm. The flow rate was 1. 0ml/min. The calibration curve was linear from 10ug/ml to 200ug/ml. The average recovery was 99. 73% (RSD =1. 22%).
出处
《西北药学杂志》
CAS
2001年第1期5-6,共2页
Northwest Pharmaceutical Journal
