摘要
The interaction of methylene blue(MB) and bovine serum albumin(BSA) is investigated in the SDS micelle system which is simulated as one kind of coexisted albumin. The interaction parameters of MB and BSA and simulated albumin such as partition coefficientκ、 normal binding free energyΔ G、 average binding number n are calculated. The results show that most of MB is in the form of monomer in SDS micelle systems； the main interaction of MB and BSA is of static electric and H-bind force,and that of MB and simulated albumin is only of static electric force.
The interaction of methylene blue (MB) and bovine serum albumin (BSA) is investigated in the SDS micelle system which is simulated as one kind of coexisted albumin. The interaction parameters of MB and BSA and simulated albumin such as partition coefficient kappa normal binding free energy Delta G(-) average binding number n are calculated. The results show that most of MB is in the form of monomer in SDS micelle systems; the main interaction of MB and BSA is of static electric and H-bind force, and that of MB and simulated albumin is only of static electric force.
出处
《物理化学学报》
SCIE
CAS
CSCD
北大核心
2001年第2期185-188,共4页
Acta Physico-Chimica Sinica
基金
国家自然科学基金 !(29733110
20073038)资助项目&&
