摘要
目的探讨腹腔镜胆囊切除术对胆结石患者超敏c-反应蛋白（hs-CRP）和胰岛素抵抗的影响。方法将106例手术治疗的胆结石患者随机分为观察组和对照组，每组53例，观察纽采用腹腔镜胆囊切除术，对照组采用小切口胆囊切除术，测定两组患者治疗前后血清hs—CRP和胰岛素抵抗指数。结果观察组手术时间、术中出血量和住院时间均少于对照组（P〈0．05）。两组术后胰岛素抵抗指数与hs—CRP均有明显升高，但对照组比观察组升高更明显（P〈0．05）。结论腹腔镜胆囊切除术比小切口手术对hs—CRP和胰岛素抵抗影响更小。
Objective To study the effect of laparoscopic cholecystectomy on high-sensitivity C- reactive protein（hs-CRP） level and insulin resistance in patients with gallstones. Methods One hundred and six patients with gallstones underwent operation were randomly divided into two groups, the observation group（53 cases） and the control group（53 cases ）. The patients in the observation group were operated through laparoscopic cholecystectomy, whil6 the patients in the control group were operated through small incision cholecystectomy. The levels of serum hs-CRP and insulin resistance indexes were measured before and after treatment. Results Operative time, blood loss volume and length of stay in the observation group were less than those in the control group （P 〈 0.05）. The postoperative insulin resistance indexes and hs- CRP levels were significantly higher, but those in the control group increased more significantly （P 〈 0. 05）. Conclusions Laparoscopic cholecystectomy affect little on the hs-CRP level and insulin resistance than small incision.
出处
《中国实用医刊》
2014年第8期59-61,共3页
Chinese Journal of Practical Medicine
关键词
胆结石
腹腔镜
超敏C-反应蛋白
胰岛素抵抗
Gallstone
Laparoscopy
High-sensitivity C-reactive protein
Insulin resistance
