摘要
【目的】观察三草舒癃汤治疗前列腺增生症(BPH)患者的临床疗效。【方法】将68例BPH患者随机分成治疗组和对照组各34例。治疗组给予三草舒癃汤治疗,对照组给予口服非那雄安(保列治)治疗,2组疗程均为12周。观察2组治疗前后临床症状积分、国际前列腺症状评分(IPPS)、最大尿流率、剩余尿量的变化情况。【结果】(1)治疗组总有效率为82.4%,对照组为76.5%,治疗组疗效优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,治疗组各症状积分均较治疗前显著下降(P<0.01);对照组只有小便频急和尿后余沥2项有改善(P<0.01),其余各项评分呈现水平波动,差异无统计学意义(P>0.05)。治疗后治疗组的中医临床症状总积分显著低于对照组,差异有统计学意义(P<0.01)。(3)治疗后,2组IPSS评分、剩余尿量均显著下降,最大尿流率均显著提高(P<0.05或P<0.01),且治疗组对上述指标的改善作用均优于对照组(P<0.05或P<0.01)。【结论】三草舒癃汤对改善前列腺增生症患者临床症状具有良好效果。
Objective To observe the clinical efficancy of Sancao Shulong Decoction for the treatment of benign prostatic hyperplasia (BPH) . Methods Sixty-eight cases of BPH were randomly divided into treatment group (N=34) and control group (N=34) The treatment group was given oral use of Sancao Shulong Decoction, and the control group was treated with western medicine Finasteride orally. The treatment course was 12 weeks for both groups. Clinical symptom scores, the International Prostate Symptom Scores (IPPS), maximum urinary flow rate (Qmax) and residual urine volume (RUV) in both groups were observed before and after treatment. Results (1) The total effective rate was 82.4% in the treatment group and was 76.5% in the control group, the difference being significant (P〈0.05) . (2) After treatment, clinical symptom scores were obviously decreased in the treatment group (P〈0.01 compared with those before treatment) . In the control group, only the scores of frequent and urgent urination and dribbling after voiding were improved (P〈0.01 compared with those before treatment) , and the scores of other symptoms showed mild changes, but the difference was insignificant (P〉 0. 05) . The symptom scores in the treatment group were much lower than those in the control group after treatment (P〈0.01) (3) After treatment, IPSS and residual urine volume were decreased, and Qmax was increased in both groups (P〈0.05 or P〈0.01) , and the improvement in the treatment group was superior to that in the control group (P〈0.05 or P〈0.01) . Conclusion Sancao Shulong Decoction exerts certain effect on relieving the clinical symptoms of benign prostatic hyperplasia patients.
出处
《广州中医药大学学报》
CAS
北大核心
2014年第2期194-197,共4页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
前列腺增生症
中药疗法
三草舒癃汤
治疗应用
Benign prostatic hyperplasia/TCD therapy
Sancao Shulong Decoction/therapeutic use