摘要
睾丸间质细胞分布于生精小管的疏松间质组织中,是产生雄性激素的主要场所。睾丸间质细胞的功能障碍是导致男性原发性性腺功能低下、隐睾、尿道下裂等疾病的重要原因,因此睾丸间质细胞对男性生殖具有重要意义。本文对近年来关于睾丸间质细胞的发生、发育及调节的研究进展予以综述。
Leydig cells, located in the loose interstitial tissue of seminiferous tubules, are the major site for androgen synthesis and secretion, and play an important role in the reproductivity and fertility of males. The dysfunction of Leydig cells may lead to various male diseases, such as primary hypogonadism, cryptorchidism, and hypospadias. This review outlines the recent findings concerning the generation, development and regulation of Leydig cells. Natl J Androl, 2014, 20 （3） ： 273 -276
出处
《中华男科学杂志》
CAS
CSCD
2014年第3期273-276,共4页
National Journal of Andrology
基金
国家自然科学基金(81270689)
上海市科委项目(12ZR1419200)~~
关键词
睾丸间质细胞
分化
调控
Leydig cell
differentiation
regulation
