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缺氧诱导因子及相关靶基因与卒中的关系研究进展 被引量：1

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摘要 缺氧诱导因子（HIF-1）是受控于氧浓度变化的一个至关重要的转录因子。在脑卒后HIF-1表达，与其下游靶基因的缺氧反应元件结合，调节其表达，介导机体的缺氧反应。本文对HIF-1及其重要靶基因（血管生长因子，热休克蛋白）在急性脑卒中的表达及临床意义进行综述。
作者 谌金花 罗永杰
机构地区 泸州医学院 四川省人民医院
出处 《西南军医》 2014年第2期166-170,共5页 Journal of Military Surgeon in Southwest China
关键词 缺氧诱导因子1 脑梗死 脑出血 血管生长因子 热休克蛋白-70
分类号 R743.34 [医药卫生—神经病学与精神病学]
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参考文献37

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二级参考文献10

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西南军医
2014年 第2期

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