摘要
目的:分析白塞病以心血管系统损害为主要表现的临床特点及超声心动图改变。方法:回顾分析2006-2012年我院以心血管病系统损害为突出表现收治且诊断白塞病的28例患者的临床资料。结果:28例患者中男性21例,女性7例,平均年龄38.8岁。以瓣膜损害为突出表现者19例,升主动脉扩张6例,以肺部损害为突出表现的5例,心腔内血栓2例,冠状动脉及心肌受累各1例。住院期间2例分别因动脉瘤破裂和肺动脉高压危象死亡。13例主动脉瓣置换术后均出现瓣周漏;1例主动脉根部置换术后效果良好;3例行心脏移植,术后早期心功能良好,无排异。结论:白塞病心血管系统受累的表现缺乏特异性。以心血管病系统损害为突出表现,尤其是青壮年非风湿性非特异性主动脉瓣膜反流,应警惕白塞病所致的瓣膜损害。
Objective： To study the clinical characteristics and echocardiographic changes in Behcet＇s patients with major element of cardiovascular involvement. Methods： We retrospectively analyzed 28 Behcet＇s patients with major element of cardiovascular involvement who were treated in our hospital from 2006 to 2012. The patients included 21 male and 7 female with the mean age of 38.8 years, their clinical diagnosis, treatment and prognosis were summarized. Results： There were 19 patients with clinical manifestations as valvular disease including 6 of ascending aortic dilatation, 5 patients with pulmonary artery involvement, 2 patients with intra cardiac thrombus, 1 with coronary artery involvement and ! with cardiomyopathy. There were 2 in-hospital death including 1 of arterial aneurysm rupture and 1 of pulmonary hypertension crisis. There were 13 patients received aortic valve replacement while all of them suffered from postoperative peri-valvular regurgitation, 1 patient received aortic root replacement with good result and 3 patients received orthotopic heart transplantation with good postoperative cardiac function. Conclusion： Behcet＇s disease with major element of cardiovascular involvement may not have specific clinical presentation. The patients, especially for youth, with non-rheumatic, non-specific aortic valve regurgitation should be alert for the etiology of Behcet＇s Disease.
出处
《中国循环杂志》
CSCD
北大核心
2014年第3期213-215,共3页
Chinese Circulation Journal
关键词
白塞病
心血管系统受累
Behcet＇s disease
Cardiovascular involvement
