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两种波长激光治疗雀斑的临床疗效对比研究 被引量:4

Comparison Between Two Different Q-Switched Nd∶YAG Lasers in Treating Freckles
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摘要 目的比较波长1 064和532 nm调Q Nd∶YAG激光治疗雀斑的临床疗效、不良反应和复发率。方法雀斑患者80例,一侧面部应用波长532nm、光斑直径2~3 mm对皮损治疗1~2次;对侧面部应用1 064 nm波长、光斑直径6~8 mm平扫皮肤治疗8次。结果波长1 064 nm治疗组,治愈70例,显效8例,好转1例,无效1例,总有效率达98.8%。波长532 nm组,治愈68例,显效10例,好转2例,无效0例,总有效率达100.0%。两种波长治愈率和总有效率比较,差异无显著意义(P〉0.05)。1 064 nm组10例(12.5%)出现不良反应,3例(3.75%)复发;532 nm组80例(100.0%)有不良反应,24例(30.0%)复发。两组治疗后不良反应和复发率比较,差异有显著意义(P〈0.05)。结论调Q Nd∶YAG激光1 064和532 nm波长治疗雀斑均有效,但前者不良反应更少,复发率低。 Objective To compare the clinical and adverse effects of 1 064 nm and 532 nm Q-Switched Nd:YAG lasers in treating Freckles.Methods Altogether 80 patients with freckles were treated with 532 nm Q-Switched Nd:YAG laser(spot diameter for point irradiation:2-3 mm) on one side of the face and 1 064 nm(spot diameter for skin scanning: 6-8 mm) on the other side.Results While the total effective rate of 1 064 nm Q-Switched Nd:YAG laser being 98.8%(70 cases fully cured,8 effectively cured,1 improved and 1 unchanged),that of 532 nm Q-Switched Nd:YAG laser stands at 100.0%(60 cases fully cured,10 effectively cured,2 improved and 0 unchanged).As to curative rate and total effective rate,there are not significant differences(P0.05) between them.However,the differences in occurrence rates(1 064 nm laser: 12.5%; 532 nm laser: 100.0%) of adverse effect and recurrence rates(1 064 nm laser: 3.75%; 532 nm laser: 30.0%) were statistically significant.Conclusions Both 1 064 nm and 532 nm Q-Switched Nd:YAG lasers are effective in treating freckles while the former being foundwith less adverse effects and lower recurrence rate.1 064 nm Q-Switched Nd:YAG laser is more acceptable to patients with freckles as no scab forms after the treatment,making daily clean-up possible such as face-washing and bath-taking.
出处 《中国激光医学杂志》 CAS CSCD 2013年第5期263-266,共4页 Chinese Journal of Laser Medicine & Surgery
关键词 激光 雀斑 治疗 Laser Freckle Treatment
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