摘要
本研究采用四水硝酸钙(Ca(NO3)2·4H2O)和磷酸氢二铵((NH4)2HPO4)分别作为钙源和磷源,以丙酰胺为pH调节剂调控溶液的过饱和度,以柠檬酸钠为钙源缓释剂调控羟基磷灰石(Hydroxyapatite,HA)的形貌,经水热法处理成功制备出高结晶度、形貌均一和分散性良好的HA微球。采用X射线衍射(XRD)、傅里叶变换红外光谱(FT-IR)和扫描电镜(SEM)对反应产物进行了表征,研究了初始pH值、柠檬酸钠加入量和水热反应温度对HA结晶度、组成及形貌的影响。研究结果表明,当初始pH值为3,柠檬酸钠与钙源的摩尔比为1︰1.5,反应温度为180℃时,有利于HA微球的形成。
Hydroxyapatite （HA） microspheres were prepared by using calcium nitrate tetra hydrate （Ca（NO3）2·4H2O） and diammonium phosphate （（NH4）2HPO4） as the resource of calcium and phosphorus, respectively. During the synthesis, propionamide was used as pH adjusting agent to control the supersaturation of the solution, and trisodium citrate was used as the calcium source relievers to control the morphology of HA. The HA microspheres with high crystallinity, regular morphology and good dispersion were synthesized through hydrothermal method. XRD, FTIR and SEM were used to characterize the product. The effects of starting pH value, the amount of trisodium citrate and reaction temperature on the crystallinity, composition and morphology of HA were investigated. The results show that the optimal condition for uniform HA microspheres was as follows, pH=3, molar ratio of sodium citrate to calcium source at about 1：1.5, and reaction temperature of 180℃.
出处
《无机材料学报》
SCIE
EI
CAS
CSCD
北大核心
2014年第3期284-288,共5页
Journal of Inorganic Materials
基金
国家973科技计划项目(2012CB619100
2011CB606204)
国家自然科学基金重点项目(51230002)
111计划(B13030)
省部产学研项目(2009B090300454)~~
关键词
水热法
羟基磷灰石
微球
柠檬酸钠
hydrothermal method
hydroxyapatite
microspheres
sodium citrate
