摘要
[目的]了解哈尔滨地区孕妇血液中有机物成分及邻苯二甲酸酯类暴露水平。[方法]随机选取哈尔滨市区和郊区健康的孕妇100名，分别采集全血2mL，并收集调查问卷表，应用气相色谱一质谱联用技术对血液中有机物成分进行定性分析，并对邻苯二甲酸酯做定量分析。[结果]孕妇全血样品中共检出有机物70种，其中邻苯二甲酸酯类4种，分别为邻苯二甲酸丁酯（DBP）、邻苯二甲酸（-乙基）己酯（DEHP）、邻苯二甲酸二异丁酯（DIBP）、邻苯二甲酸二甲酯（DMP）。市区与郊区、20岁-、30岁-组孕妇血液中4种邻苯二甲酸酯含量差异均无统计学意义。常用塑料制品打包或加热食物组孕妇血液中DBP、DIBP含量明显高于不使用组（DBP，P=0．041；DIBP，P=0．004）。[结论]哈尔滨市孕妇全血中检出多种环境有机污染物，使用塑料制品盛装或加热食物可导致孕妇血液中邻苯二甲酸酯类暴露。
[ Objective]To examine the components of organic matters and the levels of phthalates （PAEs） exposure in the whole blood of pregnant women in Harbin. [ Methods ] Whole blood （2mL） was sampled from each of 100 healthy pregnant women randomly selected from urban and suburban areas in Harbin. A face-to-face interview was conducted to collect information on general demographic characteristics and plastic exposure using questionnaires. Gas chromatography and mass spectrometry （GC/MS） was applied for qualitative analysis of organic components and quantitative analysis of phthalates. [ Results ] Seventy types of organic matters were detected in the pregnant women＇s whole blood samples, including four kinds of PAEs, i.e. dibutyl phthalate （DBP）, di- 2-ethylhexyl phthalate （DEHP）, diisobutyl phthalate （DIBP）, and dimethyl phthalate （DMP）. There were no statistical differences in the four phthalates concentrations between the urban and the suburban areas （P 〉 0.05）, nor between the 20＇s and the 30＇s age groups （P〉0.05）. The concentrations of DBP and DIBP in those who often used and heated plastic food containers were higher than those did not （DBP, P=0.041; DIBP, P=0.004）. [ Conclusion ] The pregnant women＇s whole blood contain various types of environmental organic pollutants. The usage of plastic products for heating or packing food may elevate exposure to DBP and DIBP in pregnant women＇s blood.
出处
《环境与职业医学》
CAS
北大核心
2014年第3期210-212,216,共4页
Journal of Environmental and Occupational Medicine
基金
黑龙江省厅科学技术项目(编号:12531333)
关键词
孕妇
全血
有机物
邻苯二甲酸酯
气相色谱-质谱联用
pregnant women
whole blood
organic matter
phthalates
gas chromatography and mass spectrometry
