摘要
目的通过回顾性分析既往老年非ST段抬高型急性冠脉综合征患者的病例资料,探讨全球急性冠脉综合征注册研究(The Global Registry of Acute Coronary Events GRACE)危险评分分值的高低与老年非ST段抬高型急性冠脉综合征(NSTE-ACS)患者冠脉病变状况的相关性。方法收集2012年7月—2013年3月NSTE-ACS并行冠脉造影术的65岁以上老年患者病历资料88份,依据患者入院时的年龄、血压、心率、肌酐、心肌损伤标志物、Killip分级及入院前严重心血管事件等相关基础资料,严格按照国际通行的GRACE评分标准进行评分,并依分值高低按国际通行的GRACE危险分级标准划分为低危组、中危组、高危组;以冠脉造影结果为参照标准,对比GRACE评分的高低与患者冠脉病变的相关性。结果 GRACE评分分数与与冠脉病变狭窄程度之间有正相关关系(r=0.362,P=0.001);GRACE评分分数与病变支数也呈正相关关系(r=0.262,P=0.014)。结论 GRACE危险评分能在一定程度上反映患者冠脉病变的危险程度以及病变支数。
Objective To explore the correlation between the GRACE （The Global Registry of Acute Coronary Events） Risk Score and the elderly Non ST - elevation Acute Coronary Syndrome （ NSTE - ACS ） patients＇ coronary condition through the way that retrospectively analysis the in - hospital medical history data of the elderly NSTE - ACS patients. Methods Collect the data of the elderly NSTE - ACS patients who is older than 65 and undergone coronary angiograpby surgery range from July 2012 to March 2013. A total of 88 medical history data were taken into account. We calculated the patients＇ GRACE score according to the patients＇ baseline data as age, gender, blood pressure, heart rates, creatinine, myo- cardial injury markers and the pre- hospital major adverse cardiac events ,then ranked the patients risk grade as low risk group,middle risk group and high risk group according to the international tertiles of risk grade ranking criteria depending on the GRACE risk score those patients have got, in addition, we analyze the correlation between the GRACE risk score and the elderly NSTE - ACS patients＇ coronary condition using the patients＇ coronary angiography results as reference. Results There is positive correlation between GRACE risk score and the narrowed degree of coronary artery lesions （r = 0. 362, P =0. 001 ）; Also,there got a positive correlation between GRACE risk score and the coronary artery lesion count （r = 0. 262 ,P =0. 014）. Conclusion The patients＇ GRACE risk score may reflect the narrowed degree of coronary artery le- sions and the condition of the coronary artery lesion count among the elderly NSTE - ACS patients.
出处
《医药论坛杂志》
2014年第1期7-9,共3页
Journal of Medical Forum
基金
河南省2013年医学科技攻关项目(2013-03088)
