摘要
目的比较地佐辛、曲马多、芬太尼对腹腔镜手术患者术后苏醒质量的影响。方法选择择期全麻下行腹腔镜妇科手术患者90例,采用随机数字表法分为地佐辛组(D组)、曲马多组(T组)、芬太尼组(F组)各30例,手术结束前10 min分别给予地佐辛0.1 mg/kg、曲马多2 mg/kg、芬太尼1μg/kg静脉注射。观察每组病例的拔管时间、定向力恢复时间、VAS评分、镇静评分、不良反应情况、血流动力学指标(SBP、DBP、HR)及SPO2和呼吸频率。结果与F组比较,D组和T组拔管时间缩短(P<0.01),定向力恢复时间提前(P<0.05,P<0.01);D组VAS评分低于F组(P<0.05);D组、T组镇静评分均低于F组(P<0.05);D组与T组各项指标比较,差异无统计学意义(P>0.05);F组有7例患者发生嗜睡,与D组及T组比较差异有统计学意义(P<0.05);三组患者生命体征及SpO2的比较差别无统计学意义(P>0.05)。结论腹腔镜手术结束前预注地佐辛或曲马多可缩短拔管时间及定向力恢复时间,改善苏醒质量,效果优于芬太尼。
Objective To compare the effects of Dezocine or Tramadol with Fentanyl on recovery quality in patients undergoing laparoscopie surgery. Methods Ninety patients were undergone the laparoseopic surgery with general anesthesia. The patients were randomly divided into 3 groups： Dezoeine group （group D）, Tramadol group （group T）and Fentanyl （group F） ; 30 patients in each group. In the group D, T or F, Dezocine 0. 1 mg/kg, Tramadol 2 mg/kg or Fentanyl 1 Ixg/kg were intravenously injected 10 minutes before the surgery, respectively. The extubation time, recovery time of orientation, VAS score, sedation score, adverse reaction, hemody- namincs index（ SBP, DBP and HR）, SPO： and respiration rate were recorded. Results Compared with the group F, the exttrbation time was significantly decreased in the groups D and T（P 〈 O. 01 ）. The recovery time of orientation in the group D and T was earlier than that in the group F （P 〈 O. 05 ）. Compared with the group F, the VAS score and the sedation score were decreased in the groups D and T（ P 〈 0. 05 ,P 〈 0. 01 ）. The sedation score in the group T was lower than that in the group F（ P 〈 0.05 ） and there was no significant change between the groups D and T. Compared with the groups D and T,there were seven patients with drowsiness in the group F（P 〈 0.05 ）. There was no statistically significant difference between the three groups within patients＇ vital signs and SpO2. Conclusion Injection of Dezocine or Tramadol before laparoseopie surgery can shorten the extubation time and the recovery time of orientation, and improve the quality of awakening, thereby, has a better effect than fentanyl does.
出处
《实用医院临床杂志》
2014年第2期47-50,共4页
Practical Journal of Clinical Medicine
关键词
地佐辛
曲马多
芬太尼
腹腔镜手术
苏醒质量
Dezocine
Tramadol
Fentanyl
Laparoscopie surgery
Recovery quality
