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双通道靶控丙泊酚、瑞芬太尼对全身麻醉患者苏醒质量的影响 被引量:5

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摘要 目的观察术毕持续双通道靶控输注小剂量丙泊酚、瑞芬太尼对全身麻醉患者术后苏醒质量的影响。方法40例ASAⅠ-Ⅱ级择期经鼻蝶入路垂体瘤摘除患者,随机分为靶控输注组(TCI组)与对照组(C组),每组20例。麻醉诱导采用地塞米松5 mg、咪达唑仑1 mg、芬太尼2μg/kg、丙泊酚2 mg/kg、维库溴铵0.1 mg/kg。2组麻醉维持均采用靶控泵注丙泊酚、瑞芬太尼。术毕,C组停用靶控泵注,输注等量生理盐水;TCI组持续小剂量丙泊酚(0.5-2 mg/L)、瑞芬太尼(1-2 mg/L)双通道靶控输注,待有拔管指征时拔管。记录术前,拔管前1 min,拔管即刻,拔管后15、min的SBP、DBP、HR及疼痛和躁动等不良反应发生的情况。结果TCI组拔管后心血管反应稳定,C组血压、心率在拔管前1 min、拔管即刻及拔管后1 min均较术前和TCI组升高(P〈0.05),恢复时间差异无显著性意义,但TCI组疼痛、躁动发生率明显降低(P〈0.05)。结论小剂量靶控输注丙泊酚、瑞芬太尼可有效地抑制全身麻醉患者苏醒期的心血管反应及疼痛、躁动等不良反应。
出处 《实用临床医学(江西)》 CAS 2009年第9期42-43,45,共3页 Practical Clinical Medicine
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参考文献8

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