摘要
目的 探究子宫内膜异位症患者腹腔镜术后妊娠预后相关因素及其预测术后妊娠的价值.方法 分析112例子宫内膜异位症患者腹腔镜术后随访1年内妊娠结局和术后妊娠相关因素,并采用ROC曲线分析其对妊娠结局的影响.结果 1年内39例成功妊娠,累积妊娠率34.82%,年龄、BMI、吸烟、r-AFS分期、盆腔炎症或手术史、合并输卵管阻塞、合并子宫良性病变、术后规范用药、EFI是术后妊娠的相关因素(P<0.05).经多因素Logistic回归分析,r-AFS分期、合并输卵管阻塞、术后规范用药、EFI得分是子宫内膜异位症术后妊娠的重要影响因素(P<0.05).EFI的曲线下面积为0.681 (95%CI为0.598~0.716),P<0.05,预测临界值为6分,敏感度为0.71,特异性为0.65;r-AFS分期无预测价值.结论 采用EFI进行评价可有效预测子宫内膜异位症患者腹腔镜术后妊娠结局,r-AFS分期、输卵管通畅情况、术后规范用药也对术后妊娠有显著影响.
Objective To investigate related factors and predictive value of pregnancy after laparoscopic surgery of en- dometriosis patients. Methods All 112 patients with endometriosis laparoscopy were followed up for 1 year after preg- nancy, pregnancy outcomes and related factors, and the use of ROC curve analysis analyzed its effects on pregnancy outcome. Results In 1 year 39 cases of successful pregnancy, the cumulative pregnancy rate was 34.82%, age, BMI, smoking, r-AFS stage, pelvic inflammatory disease or surgery, tubal obstruction merger, consolidation benign uterine disease, postoperative standard medication, EFI postoperative pregnancy-related factors (P 〈0.05). Multivariate Logistic regression analysis, mergers tubal obstruction, postoperative standard medication, EFI score was endometriosis preg- nancy after an important factor (P 〈0.05). The area under the curve EFI 0.681 (95% CI of 0.598-0.716), P 〈0.05, predict the critical value of 6 points, sensitivity of 0.71 and specificity of 0.65; r-AFS stage no predictive value. Conclusion EFI evaluation can effectively predict patients with endometriosis pregnancy outcome after laparoscopic surgery, r-AFS stage, tubal patency, postoperative pregnancy after standard medication also has significant influence.
出处
《中国现代医生》
2014年第8期36-39,共4页
China Modern Doctor
基金
国家自然科学基金(81070468/H0406)