摘要
[目的]探讨三丁基氯化锡（TBTCl）对僧帽牡蛎抗氧化酶系统毒性的影响程度及致毒机制。[方法]在实验室条件下，研究不同浓度（1、2、5、10和100rig／L）的三丁基氯化锡（TBTC1）在不同暴露时间（24、72、96h）对僧帽牡蛎消化腺和鳃的超氧化物歧化酶（SOD）、过氧化氢酶（CAT）和硒依赖谷胱甘肽过氧化酶（Se—GPx）活性的影响。J结果]当佃TCl浓度为1和2ng／L时，在整个实验期间TBTCl对消化腺和鳃内SOD和Se—GPx活性无显著影响（P〉0．05），而对消化腺CAT活性有显著诱导作用（P〈0．05）。当TBTcl浓度为5～100ng／L时，SOD、CAT和Se—GPx的活性都呈现不同程度的时间剂量依赖关系。[结论]该研究可为餐桌食品污染的防患、无公害水产品的生产和环境检测提供科学依据。
[ Objective ] The influencing degree of tributyhin chloride （TBTC1） on toxicity of antioxidant enzyme activity system in Ostrea cu- cuUata and its toxic mechanism. [ Method] The effects of exposing to different concentrations（ 1,2,5,10 and 100 ng/L） of TBTC1 for 24,72 and 96 h on the activity of superoxide dismutase （SOD） ,catalase （CAT） and selenium dependent glntathione peroxidase （Se-GPx） were stud- ied under laboratory conditions. [ Result] When TBTC1 concentration was 1 and 2 ng/L respectively, TBTC1 had no significant effect on the activity of SOD and Se-GPx in gills and digestive gland of O. cucullata during the whole experiment period（ P 〉 0.05 ） and had significant in- ductive effects on CAT activity in the activity of CAT in the digestive gland（P 〈0.05）. When TBTC1 concentration was 5 - 100 ng/L, the ac- tivities of SOD, CAT and Se-GPx showed different degree of time and dose dependent relations. [ Conclusion] The research could provide sci- entific basis for preventing the food pollution, the production of harmless aquatic products and environmental detection.
出处
《安徽农业科学》
CAS
2014年第4期1075-1078,共4页
Journal of Anhui Agricultural Sciences
基金
福建省科技厅青年科技人才创新项目(2008F3095)
福建省高校服务海西建设重点项目(A102)
硕士学位授予单位立项建设学科(生物学)
