摘要
目的了解江苏省2010年-2011年流行性乙型脑炎流行特点及健康人群病毒抗体水平。方法采用描述流行病学方法对2010年-2011年江苏省监测的70例乙脑病例进行分析。健康人群乙脑抗体水平的测定采用蚀斑减少中和实验，选择〈1岁、1岁-2岁、3岁～4岁、5岁-6岁、7岁～14岁、15岁～19岁、920岁共7个年龄组健康人群作为调查对象，共1410人。结果2010年和2011年江苏省乙脑年发病率分别为0．0712／10万、0．0191／10万，其中2010年死亡率为0．0039／10万。7月-9月为流行高峰。发病主要集中在7岁以下儿童。乙脑抗体总的阳性率为65．11％，几何平均滴度（GMT）为1：11．64。结论江苏省乙脑发病率维持在较低水平，发病呈明显的季节性、地域性。15岁以上人群乙脑抗体水平具有保护作用。乙脑低滴度抗体水平主要集中在小年龄组，应加强儿童免疫监测。
Objective To understand the epidemic characteristics and viral antibody level among healthy people of Japanese en- cephalitis in Jiangsu province during 2010 - 2011. Methods A total of 70 Japanese encephalitis cases were investigated using descriptive epidemiological method in Jiangsu province during 2010 -2011. One thousand, four hundred and ten healthy people were selected and divided into seven age groups ： less than one year old, 1 - 2 years old, 3 - 4 years old, 5 - 6 years old, 7 - 14 years old, 15 - 19 years old and above 20 years old, and Japanese encephalitis viral antibody was detected by plaque reduc- tion neutralization. Results The incidence rates of Japanese encephalitis were 0. 0712/100,000 and 0. 0191/100 , 000 respec- tively in 2010 and 2011 in Jiangsu province, the mortality rate was 0. 0039/100,000 in 2010. July, August and September were the epidemic peak periods. The cases concentrated on children under 7 years old. The total positive rate of Japanese encephalitis viral antibody was 65.11%, and GMT was 1 ： 11.64. Cortelusion Japanese encephalitis incidence rate remains at a low level in Jiangsu province, and the incidence shows seasonal and regional characteristics. The Japanese encephalitis antibody can exert a protective effect on persons over 15 years old. The younger children with lower Japanese encephalitis antibody level should be strengthened the immune monitoring.
出处
《中国卫生检验杂志》
北大核心
2014年第4期576-579,共4页
Chinese Journal of Health Laboratory Technology
关键词
流行性乙型脑炎
流行病学
抗体水平
血清学监测
Japanese encephalitis
Epidemiology
Antibody level
Serological monitoring
