摘要
目的：探讨肝细胞癌根治术后行辅助性肝动脉化疗栓塞对患者复发率的影响。方法对2006~2008年本院行肝癌切除术后的112例患者，按术后2个月内是否进行辅助性肝动脉化疗栓塞分为观察组（64例）和对照组（48例），对比分析两组患者术后1、2、3、4、5年的累积复发率和生存率。结果观察组1、2、3、4、5年的累积复发率分别为10.9%、44.3%、59.4%、85.6%、96.2%；对照组1、2、3、4、5年的累积复发率分别为45.8%、63.4%、80.5%、90.2%、97.3%。两组间比较术后1、2、3年差异有统计学意义（P＜0.05）；术后4、5年差异无统计学意义（P＞0.05）。结论肝细胞癌根治术后行辅助性肝动脉化疗栓塞可明显降低患者前期复发率，对后期复发率无明显作用。
Objective To analyze the effect of postoperative adjuvant transarterial chemoembolization upon recurrence after radical resection of hepatocellular carcinoma. Methods 112 patients after radical resection of hepatocellular carcinoma were divided into objective group（64 cases） and control group（48 cases）. The objective group was treated with postoperative adjuvant transarterial chemoembolization after the operation. The difference of recurrence rate between the two groups were compared. Results The recurrence rate of the objective group was 10.9%, 44.3%, 59.4%, 85.6%, 96.2%respectively at the time of first to fifth year after the operation. The recurrence rate of the control group was 45.8%, 63.4%, 80.5%, 90.2%, 97.3%respectively. There were significant differences in the data of the recurrence rate in the first to the third year. Conclusion It would get a satisfactory effect to use postoperative adjuvant transarterial chemoembolization after radical resection of hepatocellular carcinoma for reducing the recurrence rate.
出处
《中国医药科学》
2014年第2期165-167,共3页
China Medicine And Pharmacy
关键词
动脉栓塞
化疗
肝细胞癌
Postoperative adjuvant transarterial
Chemoembolization
Radical resection of hepatocellular carcinoma
