摘要
目的探讨常规治疗与常规基础上加用利尿剂呋塞米治疗高血压性心脏病合并心力衰竭发生房颤患者的疗效。方法将300例高血压性心脏病心力衰竭患者,随机分为呋塞米组150例和对照组150例,对照组采用ACEI、肠溶阿司匹林、地高辛等常规治疗,呋塞米组在常规治疗基础上加用呋塞米80mg/d,观察治疗前后心率、动态心电图、左室射血分数等指标改善情况。结果两组治疗后显效率及总有效率均无统计学差异(P>0.05),但是呋塞米组与对照组心电图相比,显效率和总有效率有统计学意义(P<0.05)。结论在常规治疗基础上加用利尿剂呋塞米,可以抑制左心室心肌纤维化,改善舒张压。
Objective To explore conventional treatment with on a regular basis and diuretic furosemide treatment of hypertensive heart disease with heart failure patients with atrial fibrillation. Methods 150 patients in the control group were treated with conventional treatment of ACEI, aspirin and digoxin. The therapy group was treated with furosemide 80 mg / d and conventional treatment. The indicators to improve the situation of the heart rate, Holter monitoring, left ventricular ejection fraction before and after treatment were observed. Results The treatment effective efficiency and total efficiency were not statistically different （P〉0. 05）. The efficiency and total efficiency of furosemide group and the con- trol group was statistically significant （P〈0.05）. Conclusion The conventional therapy and diuretic furosemide can in- hibit left ventricular myocardial fibrosis and improve diastolic blood pressure.
出处
《西部医学》
2014年第3期286-287,共2页
Medical Journal of West China
基金
国家自然科学基金(81170220)
关键词
利尿剂
高血压
心房颤动
Diuretics
Hypertension
Atrial fibrillation
