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hMLH1基因蛋白在乳腺癌组织中的表达及意义 被引量：1

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摘要 探讨人乳腺癌中hMLH1的表达及意义。采用免疫组化法分别检测60例乳腺癌及癌旁乳腺组织中hMLH1的表达情况。hMLH1在乳腺癌表达下调,在癌旁乳腺组织表达较强;hMLH1的表达情况与患者年龄、乳腺癌的临床分期以及腋窝淋巴结的转移情况均无关(P<0.05)。hMLH1基因在乳腺癌组织中表达下调,可能在乳腺癌的发生机制中起了一定的作用。
作者 郝志伟 张金库 田珊 赵文明
机构地区 河北省保定市第一中心医院普外二科 河北省保定市第一中心医院病理科 河北省保定市第一中心医院骨一科
出处 《中国现代普通外科进展》 CAS 2014年第1期60-62,共3页 Chinese Journal of Current Advances in General Surgery
关键词 乳腺肿瘤 人类错配修复基因 HMLH1
分类号 R737.9 [医药卫生—肿瘤]
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参考文献14

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二级参考文献36

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中国现代普通外科进展
2014年 第1期

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