摘要
目的观察血美安联合重组人白介素-11对聚乙二醇干扰素α-2a治疗慢性丙肝引起的血小板减少的临床疗效。方法选择60例确诊的慢性丙型肝炎患者,随机分为3组,分别使用重组人白介素-11、血美安、血美安联合重组人白介素-11治疗。3周后观察疗效。结果重组人白介素组-11有效率为85.00%,血美安组有效率为68.42%,血美安联合重组人白介素-11组有效率为90.47%,联合组明显优于其余两组(P<0.05),重组人白介素-11组优于血美安组(P<0.05)。结论聚乙二醇干扰素α-2a治疗慢丙肝引起的血小板减少,血美安联合重组人白介素-11更能提高疗效,减少不良反应。
Objective To observe of the effect of Xuemeian combined with recombinant human interleukin - 11 on pegylated interferon α - 2a in treatment of chronic hepatitis C caused by thrombocytopenia curative effect observation. Methods 60 patients with chronic hepati- tis C, divided into 3 groups, one with recombinant human interleukin - 11, single Xuemeian group, the effect of Xuemeian combined with recombinant human interleukin - 11 group. Results Recombinant human interleukin - 11 efficiency is 85%, the effect of Xuemeian group effective rate is 68.42%, the effect of Xuemeian combined with recombinant human interleukin - 11 group was 90.47%, there was signifi- cant difference between three groups （ P 〈 0.05 ）, in which the effect of Xuemeian combined with recombinant human interleukin - 11 group was signifieantly superior to the single use of Xuemeian group and use of recombinant human interleukin - 11 group, while the single use of recombinant human inter/eukin - 11 group is better than the effect of Xuemeian group. Conclusion Pegylafed interferon a - 2a in treatment of ehronie hepatitis C caused by thromboeytopenia, Xuemeian combined with recombinant human interleukin - 11 can improve the eurative effect, reduce the adverse reaction.
出处
《湖北中医药大学学报》
2014年第1期33-35,共3页
Journal of Hubei University of Chinese Medicine
关键词
慢性丙型肝炎
中西医结合疗法
血美安胶囊
重组人白介素-11
chronic hepatitis C
integrated Chinese - western therapy
Xuemei ＇ an capsule
recombinant human interleukin 11
