摘要
目的：探讨发展性照顾对早产儿胃肠、免疫功能成熟度的影响。方法将100例早产儿按随机数字表法分为常规组、观察组各50例，两组均采用常规治疗护理措施，常规组在不能经口喂养期间给予非营养性吸吮，观察组给予发展性照顾，选取40例同期出生的足月儿为对照组，比较观察组和常规组早产儿血胃泌素（ GAS）、恢复出生体重所需时间、院内感染发生率，并比较早产儿与对照组IgM、IgG水平。结果出生时两组 GAS比较，差异无统计学意义（ P＞0．05）；出生5 d常规组早产儿GAS为（115．59±25．87）ng/L，低于观察组的（138．52±26．62）ng/L，差异有统计学意义（t＝4．37，P＜0．01）；出生10 d常规组早产儿IgG、IgM分别为（83．56±21．17），（1．54±0．62） Ug/ml，观察组分别为（91．19±21．29），（1．78±0．62）Ug/ml，两组比较差异无统计学意义（t分别为1．80，1．93；P＞0．05）；观察组恢复出生体重所需时间为（9．12±2．1）d，少于常规组的（12．00±2．12）d，差异有统计学意义（t＝6．68，P＜0．01）；观察组院内感染发生率为0．98‰，常规组为3．94‰，差异无统计学意义（χ2＝0．84，P＞0．01）。结论发展性照顾可促进早产儿胃泌素的释放，促进胃肠功能成熟及体重增长，但短期对免疫功能无明显促进作用。
Objective To explore the effect of development care on promoting the maturity of gastrointestinal and immunologic function in the premature infants .Methods One hundred premature infants were randomly divided into the conventional group and the experimental group according to the random number table, each with 50 cases.The two groups received the routine nursing measures , and the conventional group received the non-nutritive sucking during the non-oral feeding period , while the experimental group received development care .The levels of gastrin （ GAS） , IgG and IgM were compared between two groups , and the time required for recovery of birth weight and the incidence rate of nosocomial infection were also compared . Results No difference was found in the level of blood GAS at the birth （P＆gt;0.05）.The level of GAS in the conventional group was （115.59 ±25.87） ng/L five days after the birth, and was lower than （138.52 ± 26.62）ng/L in the experimental group, and the difference was statistically significant （t=4.37, P＆lt;0.01）. The levels of IgG and IgM in the conventional group were respectively （83.56 ±21.17） and （1.54 ±0.62）Ug/ml ten days after the birth, and were respectively （91.19 ±21.29） and （1.78 ±0.62） Ug/ml in the experimental group, and the difference was not statistically significant （t =1.80, 1.93, respectively; P〈0.05）.The time required for recovery of birth weight in the experimental group was （9.12 ±2.1） d, and was less than （12.00 ±2.12） d in the conventional group , and the difference was statistically significant （ t =6.68, P〈0.05）.The incidence rate of nosocomial infection was 0.98‰ in the experimental group, and was 3.94‰ in the conventional group, and there was no statistically significant difference （χ2 =0.84, P 〈0.05 ）. Conclusions Development care can promote the release of gastrointestinal hormones in premature infants , and also promote the maturity of gastrointestinal function and the increase in weight growth , and has no obvious role in promoting the maturity of immunologic function .
出处
《中华现代护理杂志》
2014年第2期155-157,共3页
Chinese Journal of Modern Nursing
基金
2011年度吴江市社会发展项目（WS201134）
关键词
早产儿
发展性照顾
胃泌素
体液免疫
院内感染
Premature infants
Developmental care
Gastrin
Humoral immunity
Nosocomial infection
