慢性心力衰竭患者脑钠肽水平检测意义分析被引量：22

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摘要目的:探讨慢性心力衰竭脑钠肽变化规律及对预后的影响。方法:回顾性分析176例CHF患者临床资料,观察脑钠肽水平;分析CHF患者不同心功能分级脑钠肽水平与LVEDd、LVEF相关性,比较高脑钠肽和脑钠肽正常CHF患者预后差异。结果:CHF患者脑钠肽(472.34±165.22)pg/mL,高脑钠肽130例(73.86%),随着心功能分级增加脑钠肽水平升高,高脑钠肽患者相应增加(P<0.05),脑钠肽升高LVEDd增加、LVEF降低(P<0.05),随访(2.05±0.77)年,高脑钠肽组死亡13.85%、住院(3.05±0.88)次/年、住院时间(51.89±13.04)d/年高脑钠肽正常组的2.17%、(1.61±0.65)次/年、(30.28±8.23)d/年(P<0.05)。结论:CHF高脑钠肽发生率较高,对预后有不良影响,脑钠肽可作为心力衰竭的血浆标志物,可用于CHF的严重程度及预后评估。

作者张日金玲张宏伟李先馨

机构地区河北省承德钢铁集团有限公司职工医院

出处《河北医学》 CAS 2014年第2期351-352,共2页 Hebei Medicine

关键词慢性心力衰竭脑钠肽检测

分类号 R541.6 [医药卫生—心血管疾病]

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1符震球,顾光大.检测尿B型利钠肽在心力衰竭诊断中的意义[J].医学研究杂志,2013,42(1):162-166. 被引量：4
2张犁.脑钠肽对高血压合并心力衰竭预后的临床评估[J].中国实用医刊,2013,40(2):108-108. 被引量：4
3曹丹阳,毕磊,裴志勇,武云涛,陈艳梅,曹晶晶.脑钠肽水平对老年心力衰竭患者的诊断价值[J].浙江临床医学,2013,15(1):61-62. 被引量：3

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