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伊立替康联合顺铂治疗晚期食管癌临床观察 被引量:1

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摘要 目的探讨伊立替康(CPT-11)联合顺铂(DDP)方案治疗晚期食管癌的临床效果。方法初治晚期食管癌患者37例,治疗方案为IP(CPT-11+DDP),治疗期间常规给予其止吐、利尿、水化等对症支持治疗,至少完成2个周期规范化疗后进行疗效评估,并记录治疗期间的不良反应。结果有效率为51.4%,控制率为83.8%。主要不良反应为恶心、呕吐,其次为骨髓抑制、腹泻、肝功能损害。结论IP方案在治疗晚期食管癌效果显著,治疗过程中的不良反应经对症治疗后均可改善,临床上患者可以耐受,值得临床推广应用。
出处 《中国实用医刊》 2014年第6期104-105,共2页 Chinese Journal of Practical Medicine
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