摘要
目的探讨儿童偏头痛的临床特点及氟桂利嗪的治疗作用。方法选择82例儿童偏头痛患者为研究对象，并进行影像学、脑电图及多普勒检查（TCD），分析儿童偏头痛的临床特点。给予患儿氟桂利嗪口服，疗程1个月，治疗结束后评估临床疗效。结果82例儿童偏头痛患者男女比例为40：42，头痛持续时间为1～63（6．59±1．38）h；其中有家族史者56例（68．3％）；疼痛常见部位依次为：前额、双侧额颞部及单侧额颞部；恶心呕吐及畏光是最常见的伴随症状；TCD提示30例患儿脑动脉血流速度异常，脑电图8例患儿散在局灶棘慢波；氟桂利嗪治疗有效率为89．0％，TCD提示治疗后大脑中动脉（MCA）、大脑前动脉（ACA）、大脑后动脉（PCA）、椎动脉（VA）及基底动脉（BA）血流均显著改善（P〈O．05）。结论儿童偏头痛男女发病比例接近，诊断主要依据临床表现，氟桂利嗪治疗效果理想。
Objective To explore the clinical characteristics of children migraine and the clinical effect of flunariz- inc. Methods 82 children with migraine measured with iconography, encephalogram and TCD were selected as research sub- jects. The clinical characteristics were studied. All the patients received flunarizine treatment. The course of treatment was 1 month. Clinical effects were evaluated after treatment. Results The male/female ratio was 40 ： 42 ; Headache duration was 1 63（6.59± 1.38）h;68.3 % children had family history. The common sites of headache were forehead, bilateral frontotemporal and unilateral frontotemporal lobe; Nausea, vomitting and photophoby were the common accompanying signs in the patients; 30 cases showed abnormal blood flow velocity in TCD and 8 cases appeared dispersive abnormal focal spikes in slow-wave of en- cephalogram. The effective rate of treatment was 89.0%; Blood flow velocity of MCA, ACA, PCA, VA and BA after treat- ment greatly improved（P（0.05）. Conclusion The occurrence of children migraine is similar in male or female. The diagnosis is mainly according to clinical manifestation. The effect of flunarizine for children migraine is ideal.
出处
《中国实用神经疾病杂志》
2014年第4期41-42,共2页
Chinese Journal of Practical Nervous Diseases
关键词
偏头痛
儿童
临床特点
氟桂利嗪
Migraine
Children
Clinical characteristics
Flunarizine
