摘要
目的探讨激素联合丙种球蛋白治疗吉兰-巴雷综合征的临床效果。方法选择我院收治的30例吉兰-巴雷综合征患者的临床资料,其中观察组15例患者采用激素联合丙种球蛋白治疗,对照组15例采用激素治疗,比较2组患者的临床效果。结果观察组总有效率86.67%,明显高于对照组,差异具有统计学意义(χ2=5.454,P=0.019<0.05)。观察组上下肢评分均较对照组出现显著改善,差异有统计学意义(P<0.05),观察组患者的肌力起效时间和住院时间分别为(3.76±1.33)d、(22.01±2.97)d,均明显优于对照组,差异均有统计学意义(P<0.05)。结论采用激素联合丙种球蛋白治疗吉兰-巴雷综合征疗效显著,有利于患者早期康复,值得临床应用。
Objective To investigate the clinical efficacy of gamma globulin combined with hormone on Guillain-Barre syn- drome. Methods 30 patients with Guillain-Barre syndrome were divided into two groups： the observation group with 15 cases received gamma globulin combined with hormone and the control group with 15patients received only hormone treatment. The clinical efficacy of two groups were compared. Results After treatment, the total effective of observation group was 86, 67~, significantly higher than that of control group,and difference between two groups was statistically significant （x2 = 5. 454, P = 0. 019） ; the score of upper and lower limbs in observation group were better than those in the control group patients, and difference was statistically significant （P〈0.05）; onset time of muscle strength and hoptia[ stays in observation group was （3.76 ± 1.33）d and （22.01 ± 2.97）d, significantly better than those in control group, and the differences were statistically sig- nificant （P〈0.05）. Conclusion Gamma globulin combined with hormone has a very significant efficacy on Guillain-Barre syn- drome, which is conducive to early rehabilitation of the patients, and it is worthy of clinical application.
出处
《中国实用神经疾病杂志》
2014年第4期23-25,共3页
Chinese Journal of Practical Nervous Diseases
