摘要
格林巴利综合征是一种神经系统自身免疫性疾病。迄今为止,病因仍不十分清楚,普遍认为微生物感染、疫苗接种、自身免疫状况、遗传、营养状况等因素与其发病有关。其发病率随地区、年龄、性别、人群、时期、国家等因素的变化而变化。许多疫苗和格林巴利综合征有联系,但一直没有因果关联性结论。本文通过检索近些年国内外发表的论文,介绍了疫苗和格林巴利综合征的研究进展,并提出了影响疫苗和格林巴利综合征关联性判定的因素。
Guillain-Barré Syndrome（GBS） is an autoimmune disorder of nerves.Although the aetiology of GBS is not completely understood,it is broadly believed that lots of factors associated with it,such as infection,vaccination,immunization,genetic,nutrition,et al.The background rates of GBS change with region,age,gender,race,times and nations.There are many vaccines have temporal association with GBS.But causal association between them is not concluded.In this paper,the research progress about association between vaccination and GBS had been introduced through searching the papers published latest years.The factors which influence determining the association between vaccines and GBS are listed in the paper.
出处
《中国药物警戒》
2011年第9期549-552,共4页
Chinese Journal of Pharmacovigilance
基金
科技部课题资金资助项目(2009ZX10004-806)
关键词
疫苗
格林巴利综合征
vaccine
Guillain-Barré Syndrome
