摘要
目的探讨强化干预对乙型肝炎(乙肝)肝硬化抗病毒治疗依从性的影响。方法将2007年1月-2009年1月100例行抗病毒治疗的乙肝肝硬化患者随机分为干预组和对照组,每组各50例。对照组给予常规护理,干预组在常规护理的基础上,加强病情宣教、用药指导,并于出院后每周电话随访。在患者出院后的第6、12、18、24、30、36个月采用自行设计的乙肝肝硬化患者抗病毒治疗遵医行为调查问卷表进行随访,比较两组患者完全遵医、不完全遵医、完全不遵医的发生比例并分析其中的原因。结果出院后的18个月内两组依从性差异无统计学意义(P>0.05),而在第24、30、36个月时,两组依从性差异均有统计学意义(P<0.05)。不遵医的原因主要为费用高和疗效不理想,在对照组患者用药依从性差的原因还有缺乏肝硬化疾病知识以及缺乏用药指导和监督。结论在抗病毒治疗过程中通过强化护理干预,患者的治疗依从性明显提高。
Objective To investigate the influence of strengthening intervention on antiviral treatment compliance for cirrhosis patients following chronic hepatitis B. Methods One hundred patients with cirrhosis following chronic hepatitis B undergoing antiviral treatment between January 2007 and January 2009 were randomly divided into intervention group and control group with 50 patients in each group. Patients in the control group received routine care. For patients in the intervention group, besides routine care, strengthening education on the disease, medication guide, and weekly telephone follow-up after discharge were also added. On the time points of 6, 12, 18, 24, 30, 36 months after patients were discharged, we followed them up with self-designed questionnaire, and compared the two groups of patients on the rates of fully complying with doctors, not fully complying with doctors and completely not complying with doctors. And the reasons were also analyzed. ResuRs Eighteen months after being discharged, the two groups had no significant difference in the rate of complying with doctors （P 〉 0.05）, while the difference was significant 24, 30, 36 months after leaving the hospital （P 〈 0.05）. The reasons were not following the doctors were mainly high cost and unsatisfying treatment effect. In the control group, the reasons also included lack of knowledge about the disease and lack of guidance and supervision. Conclusion Through strengthening nursing intervention, patients＇ treatment compliance can be improved significantly.
出处
《华西医学》
CAS
2014年第2期311-314,共4页
West China Medical Journal
关键词
乙型肝炎
肝硬化
抗病毒
强化干预
治疗依从性
Hepatitis B
Liver cirrhosis
Antiviral
Strengthening intervention
Treatment compliance
