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胰腺腺泡细胞癌的CT和MRI表现 被引量:11

CT and MRI features of acinar cell carcinoma of the pancreas
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摘要 目的:分析胰腺腺泡细胞癌(ACC)的CT和MRI表现,提高对该病的认识。方法:回顾性分析经手术病理或穿刺活检证实的5例ACC患者的CT和MRI表现。5例均行CT平扫及增强扫描,2例行MRI检查。实验室检查甲胎蛋白(AFP)升高2例。结果:5例ACC中,4例单发,1例多发。2例位于胰头钩突部,2例位于胰尾部,1例多发肿瘤位于胰头及胰尾部。肿瘤平均最大径4.0cm。2例形态不规则,2例呈卵圆形,1例可见浅分叶。1例肿瘤可见完整包膜。4例肿瘤以实性成分为主,1例呈囊实性(中央囊性伴出血坏死)。1例伴钙化。5例肿瘤CT平扫均呈不均匀低密度,动脉期呈轻度不均匀强化,门脉期强化程度较动脉期略增高,但低于周围正常胰腺。2例MRI扫描示病灶在压脂T1WI上为均匀低信号,压脂T2WI上为不均匀略高信号。3例伴胰管扩张,其中1例伴低位胆管梗阻。结论:ACC可有完整包膜,可伴出血坏死和钙化,增强呈渐进性强化,较少引起胰胆管阻塞,实验室检查可提示AFP升高。 Objective: To analyze the CT and MRI findings of acinar cell carcinoma (ACC) of the pancreas in order to determine the imaging significance of this rare condition. Methods:CT and MRI findings in 5 patients with histologically ver- ified pancreatic ACC were retrospectively reviewed. All cases underwent both p!ain and contrast enhanced CT scan. Two of them also had MRI scan. Reslllts:Of the 5 cases,four were of single lesion,two of them were found in the head of the pan- creas and the other two lesions were in the tail;one case was of multiple lesions found both in the head and the tail. The mean diameter was 4cm. Two lesions showed irregular shape,two had ovoid shape,and one was mildly lobulated. Only one lesion had a complete capsule. Four tumors were mainly solid and one was centrally cystic with hemorrhage. One mass had calcification inside. All five tumors showed relatively uneven lower density and moderate enhancement in arterial phase and slightly higher on portal venous phase, but still lower than normal surrounding pancreatic tissue. Two masses showed even low signal on fat-saturation T^WI and moderately uneven high signal on fat-saturation T2WI. Dilated pancreatic duct was seen in three cases and one of which was with low biliary obstruction. Serum ^-fetoprotein (AFP) was tested positively in two cases. Conclusion:Pancreatic ACC typically presents as a round-like mass which may have complete capsule and,some- times, hemorrhage, necrosis, significant central hypodentsity and internal calcifications. The mass usually shows progressive enhancement after contrast injection. It seldom causes low biliary obstruction. It is a useful clue to the diagnosis of ACC by understanding the above mentioned imaging features combined with elevated serum a-fetoprotein.
出处 《放射学实践》 2014年第2期181-184,共4页 Radiologic Practice
关键词 胰腺肿瘤 体层摄影术 X线计算机 磁共振成像 Pancreas neoplasms Tomography, X-ray computed Magnetic resonance imaging
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参考文献6

  • 1Kitagami H,Kondo S,Hirano S. Acinar cell carcinoma of the pancreas:clinical analysis of 115 patients from the Pancreatic Cancer Registry of Japan Pancreas Society[J].PANCREAS,2007,(01):42-46.
  • 2Holen KD,Klimstra DS,Hummer A. Clinical characteristics and outcomes from an institutional series of acinar cell carcinoma of the panereas and related tumors[J].Journal of Clinical Oncology,2002,(24):4673-4678.
  • 3Jang SH,CHoi SY,Min JH. A case of acinar cell carcinoma of pancreas,manifested by subcutaneous nodule as initial clinical symptom[J].Korean Journal of Gastroenterology,2010,(02):139-143.
  • 4Seth AK,Argani P,Campbell KA. Acinar cell carcinoma of the pancreas:an institutional series of resected patients and review of the current literature[J].Journal of Gastrointestinal Surgery,2008,(06):1061-1067.
  • 5Tatli S,Mortele KJ,Levy AD. CT and MRI features of pure acinar cell carcinoma of the pancreas in adults[J].American Journal of Roentgenology,2005,(02):511-519.
  • 6Chiou YY,Chiang JH,Hwang JI. Acinar cell carcinoma of the pancreas:clinical and computed tomography manifestations[J].Journal of Computer Assisted Tomography,2004,(02):180-186.

同被引文献58

  • 1Tatsuaki Sumiyoshi,Yasuo Shima,Takehiro Okabayashi,Akihito Kozuki,Toshio Nakamura.Comparison of pancreatic acinar cell carcinoma and adenocarcinoma using multidetector-row computed tomography[J].World Journal of Gastroenterology,2013,19(34):5713-5719. 被引量:6
  • 2石怀银,韦立新,李向红,笪冀平.胰腺腺泡细胞癌14例临床病理分析[J].临床与实验病理学杂志,2005,21(4):419-421. 被引量:14
  • 3Schmidt CM, Matos JM, Bentrem DJ, et al. Acinar cell carcinoma of the pancreas in the United States:prognostic factors and comparison to ductal adenocarcinoma [ J]. J Gastrointest Surg,2008,12 ( 12 ) : 2078 - 2086.
  • 4Riechelmann RP, Hoff PM, Moron RA, et al. Acinar cell carcinoma of the pancreas [ J ]. Int J Gastrointest Cancer,2003,34 ( 2/3 ) :67.
  • 5Wisnoski NC,Townsend CM, Nealon WH, et al. 672 patients with acinar cell carcinoma of the pancreas : a population-based comparison to pancreatic adenocarcinoma [ J ]. Surgery,2008,144 ( 2 ) : 141.
  • 6Chiou Y, Chiang JH, Hwang JI, et al. Acinar cell carcinoma of the pancreas: clinical and computed tomography manifestations [ J ]. J C omput Assist Tomogr, 2004,28 ( 2 ) : 180 - 186.
  • 7Chetty R, E1-Shinnawy I. Intraductal pancreatic neuroendocrine tumor [ J ]. Endocri Patho1,2009,20 (4) :262 - 266.
  • 8I-Iolen KD, Klimstra DS, Hummer A, et aL Clinicai characteristics and outcomes from an institutional series of acinar cell carcinoma of the pancreas and related tumors [ J ]. J Cliu Oncol, 2002,20 ( 24 ) : 4673 - 4678.
  • 9Seki Y, Okusaka T, Ikeda M, et al. Four cases of pancreatic acinar cell carcinoma treated with gemcitabine or S-I as a single agent [ J ]. Jpn J Clin Oneol,2009,39( 11 ) :751 -755.
  • 10CHAUDHARY P, RAN JAN G, CHAUDHARY A, et al. Ac- inar cell carcinoma: a rare pancrea-tic malignancy [J]. Clin Pract, 2013, 3(2): el8.

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