期刊文献+

血液灌流在儿童重型皮肌炎治疗中的应用 被引量:3

The application of hemoperfusion in severe juvenile dermatomyositis
暂未订购
导出
摘要 目的观察血液灌流治疗儿童重型皮肌炎的效果。方法回顾性分析2例重型皮肌炎接受血液灌流治疗患儿的临床资料。结果 2例患儿血液灌流过程顺利,灌流后肌痛症状明显好转,肌酶明显下降;其中1例患儿在血液灌流后拒绝接受治疗,病情反复;另1例患儿灌流后继续给予免疫抑制剂等积极治疗,最终好转出院。结论血液灌流可以作为重型皮肌炎的辅助治疗方法,可用于一般治疗无效者。 Objectives To investigate the clinical effect of hemoperfusion in severe juvenile dermatomyositis. Meth-ods Two patients with severe juvenile dermatomyositis, who accepted hemoperfusion treatment, were retrospectively analyzed. Results In these 2 patients, the hemoperfusion process were smooth. The muscle pain was reduced and the muscle enzymes were decreased. After hemoperfusion, one patient refused to continue treatment and the disease recurrent. The other patient con-tinued to accept the immunosuppressive therapy and eventually improved. Conclusions For juvenile dermatomyositis, hemo-perfusion was a safe and effective auxiliary treatment. It could be applied when the general treatment was invalid.
出处 《临床儿科杂志》 CAS CSCD 北大核心 2014年第2期144-146,共3页 Journal of Clinical Pediatrics
关键词 皮肌炎 血液灌流 儿童 dermatomyositis hemoperfusion child
  • 相关文献

参考文献3

二级参考文献27

  • 1季雅娟,骆仲智.儿童皮肌炎[J].中国麻风皮肤病杂志,2005,21(7):549-551. 被引量:5
  • 2程志祥,刘宝瑞.Th1/Th2漂移与肿瘤免疫治疗[J].江苏医药,2006,32(6):567-568. 被引量:12
  • 3肇毅,陆森,成峰,华一兵,吴文溪.Th1和Th2细胞因子在诱导肝肠联合移植免疫耐受中的作用[J].江苏医药,2006,32(10):938-940. 被引量:7
  • 4Ohtsuka K, Dixon J, Mary M et al. Decreased production of TGF-β by lymphocytes from patients with systemic lupus erythematosus[J] .J Immunol, 1998; 160:2539-2545.
  • 5Amemiya K, Semino M C, Granger R P et al. Downregulation of TGFbetal mRNA and protein in the muscles of patients with inflammatory myopathies after treatment with high-dose intravenous inmmunonglobulin[J].Clin Immunol,2000;94(2) :99-104.
  • 6张素英,刘玉阁,纪岩文,崔平津.皮肌炎/多发性肌炎患者血清Jo-1抗体检测的临床意义[J].临床皮肤科杂志,1997,26(2):81-83. 被引量:6
  • 7Grundtman C, MalmstrOm V, Lundberg IE, etal. Immune mechanisms in the pathogenesis of idiopathic inflammatory myopathies[J]. Arthritis Res Ther, 2007,9(2) : 208-220.
  • 8Takahashi S, Fossati L, Iwamoto M, et al. Imbalance towards Thl predominance is associated with acceleration of lupus like autoimmunesyndrome in MRL mice[J]. Clin Invest, 1996,97 (7): 1597-1604.
  • 9Caproni M, Torchia D, Cardinali C, et al. Infiltrating cells, related cytokines and chemokine receptors in lesion skin of patients with dermatomyositis [ J ]. Br J Dermatol, 2004, 151 (4):784-791.
  • 10Mariapaola M, Flavia S, Francesca M, et al. TGF-β1 and IL10 modulate IL-1βinduced membrane and soluble ICAM-1 in human myoblasts[J]. Journal of Neuroimmunology, 2003, 134(1):151-157.

共引文献9

同被引文献42

  • 1金德蕙.青霉素致皮肌炎1例[J].中国麻风皮肤病杂志,2005,21(3):208-208. 被引量:2
  • 2谢瑶,王国春.静脉注射免疫球蛋白治疗特发性炎性肌病的研究进展[J].中华风湿病学杂志,2005,9(7):431-433. 被引量:4
  • 3罗薇,张英泽,阎小萍.中药使君子致皮肌炎[J].药物不良反应杂志,2007,9(1):56-57. 被引量:6
  • 4朱才勇.注射流感疫苗致皮肌炎复发1例[J].皮肤病与性病,2007,29(2):61-61. 被引量:3
  • 5薛彦忠.诺氟沙星致多发性皮肌炎1例[J].中国新药杂志,1996,5(6):466-466.
  • 6Baechler EC, Bilgic H, Reed AM. Type I interferon path- way in adult and juvenile dermatomyositis [ J 1- Arthritis Res Ther, 2011,13 (6) : 249.
  • 7Hirayama,F.Current understanding of allergic transfusion reactions:Incidence,pathogenesis,laboratory tests,prevention and treatment[J].Br J Haematol,2013,160(4):434-444.
  • 8Mcguckin S,Westwood JP,Webster H,et al.Characterization of the complications associated with plasma exchange for thrombotic thrombocytopaenic purpura and related thrombotic microangiopathic anaemias:a single institution experience[J].Vox Sang,2014,106(2):161-166.
  • 9OBrien.L K,Price.The use of 50%albumin/plasma replacement fluid in therapeutic plasma exchange for thrombotic thrombocytopenic purpura[J].J Clin Apher,2013,28(6):416-421.
  • 10中华人民共和国国家卫生和计划生育委员会.药品不良反应报告和监测管理办法[s].[2011]81号.

引证文献3

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部