摘要
目的:探讨通窍鼻炎颗粒治疗鼻窦炎的临床疗效及安全性。方法:240例鼻窦炎患者随机分为两组各120例。观察组患者予通窍鼻渊颗粒1袋,tid;对照组患者予布地奈德鼻喷雾剂每侧鼻腔喷100μg,qd。两组患者均治疗3周后,观察疗效及不良反应。结果:治疗后,观察组患者鼻塞、流涕、头痛、咳嗽等症状体征改善情况显著优于对照组(P<0.05),总有效率显著高于对照组(P<0.05)。两组患者治疗过程中均未见明显不良反应。结论:通窍鼻渊颗粒治疗鼻窦炎疗效显著,安全性好,值得临床推广使用。
Objective： To evaluate the clinical efficacy and safety of Tongqiao Biyan granules in the treatment of sinusitis. Methods： Totally 240 cases of sinusitis were randomly divided into two groups, each group had 120 cases. The patients in observation group were treated with 1 bag of Tongqiao Biyuan granules, 3 times a day, while the patients in control group were treated with busesonide nasal spray 100 μg each side nasal cavity, once a day. After 3 weeks,curative effect and adverse drug reaction of the two groups were observed. Results：After the treatment, nasal congestion, runny nose, headache, cough and other signs and symptoms were improved more significantly in the observation group than those in the control group （P〈0.05）, the total effective rate of the observation group was 92.5%, while that of the control group was 79.2%, the difference was significant （P〈0.05）. During the treatment, the two groups showed no obvous adverse drug reactions. Conclusion： The effect of Tongqiao Biyuan granules in the treatment of sinusitis is significant with no obvious adverse drug reactions, which should be recommended to use in clinic.
出处
《中国药师》
CAS
2014年第2期264-266,共3页
China Pharmacist
关键词
通窍鼻炎颗粒
鼻窦炎
布地奈德鼻喷雾剂
疗效
Tongqiao Biyan granules
Sinusitis
Budesonide nasal spray
Therapeutic effect
