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复发性泌尿系结石患者24h尿枸橼酸盐含量的病例对照研究及结石成分分析 被引量:11

Case-control study of 24-hour urinary citrate excretion in patients with recurrent urinary calculi and analysis of stone composition
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摘要 目的:分析复发性泌尿系结石患者尿枸橼酸排泄量与结石成分及微观形态,探讨泌尿系结石形成与复发的防治措施。方法:采用病例对照的研究方法,比较复发性泌尿系结石患者与对照组之间的尿枸橼酸排泄量,并运用红外光谱、X线衍射及扫描电镜分析复发性结石的成分与微观形态。结果:复发性结石患者尿枸橼酸排泄量显著低于对照组。结石的成分以草酸钙(80%)和尿酸结石(33%)为主。结论:结石患者术后的代谢分析、严格随访和适量的枸橼酸盐补充,可能在一定程度上降低泌尿系结石的复发率。泌尿系结石的成分分析可为制定预防结石复发方案提供理论依据。 Objective: To analyze 24-hour urinary citrate excretion and stone composition of recurrent urinary calculi patients. Method: The case-control study was conducted to compare 24-hour urinary eilrate excretion be- tween the recurrent urinary calculi patients and normal people who recovered from urinary calculi. ]n[rared spec- troscopy, X-ray diffraction and scanning electron microscope were used for analyzing the micromorphology and composition of stones. Result: 24-hour urinary citrate excretion in patients with recurrent urinary calculi was sig- nificantly lower than normal people who recovered from urinary calculi, and the main composition were calcium ox- alate (809/0 ) and uric acid (33 ~ ). Conclusion: Metabolism analysis, strict follow-up and appropriate supply of cit- rate may decrease the recurrence rate of urinary calculi. The result of composition of stones can be accepted as a theoretical base for preventive guidelines of urinary calculi.
出处 《临床泌尿外科杂志》 2014年第2期108-112,共5页 Journal of Clinical Urology
基金 三亚市医疗卫生科技创新项目(编号YW1312)
关键词 复发性泌尿系结石 枸橼酸盐 结石成分 病例对照研究 recurrent urinary calculi citrate stone composition~ case-control study
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参考文献15

  • 1L6pez M, Hoppe B. History, epidemiology and region- al diversities of urolithiasisEJ]. Pediatr Nephrol, 2010, 25(1) : 49-59.
  • 2Brikowski T H, Lotan Y, Pearle M S. Climate-related increase in the prevalence of urolithiasis in the United StatesEJ]. Proc Natl Acad Sci U S A, 2008, 105(28): 9841-9846.
  • 3Worcester E M, Coe F L. Clinical practice. Calcium kidney stonesEJ]. N Engl J Med, 2010, 363(10): 954 -963.
  • 4Caudarella R, Vescini F. Urinary citrate and renal stone disease., the preventive role of alkali citrate treat- ment[J]. ArchltalUrol Androl, 2009, 81(3): 182- 187.
  • 5Mithani S, Zaidi Z. Comparison of 24 hours urinary citrate levels in urolithiasis patients and healthy con- trois[J]. J Pak Med Assoc, 2005, 55(9): 371-373.
  • 6Sakhaee K. Recent advances in the pathophysiology of nephrolithiasis[J]. Kidney Int, 2009, 75(6): 585- 595.
  • 7Grases F, Costa-Bauza A, Prieto R M. Renal lithiasis and nutrition[J]. Nutr J, 2006, 5: 23.
  • 8GOkta~ C, Horuz R, Akca O, et al. The effect of cit rate replacement in hypoeitraturic cases on the results of SWL: a preliminary prospective randomized study [J]. Int Urol Nephrol, 2012, 44(5): 1357-1362.
  • 9Amaro C R, Goldherg J, Amaro J L, et al. Metabolic assessment in patients with urinary lithiasis[J]. Int Braz J Urol, 2005, 31(1): 29-33.
  • 10Ekeruo W O, Tan Y H, Young M D, et al. Metabolic risk factors and the impact of medical therapy on the management of nephrolithiasis in obese patients[J]. J Urol, 2004, 172(1): 159-63.

同被引文献74

  • 1郭小林,叶章群,杨为民,刘继红,张旭,庄乾元,陈志强,周惜才,周四维.输尿管镜在泌尿外科中的应用[J].中国内镜杂志,2005,11(11):1172-1174. 被引量:9
  • 2石海燕,刘东亮,卢一平,周开华,朱蜀侠,吕健为.钬激光结合输尿管镜治疗泌尿系结石[J].临床泌尿外科杂志,2006,21(7):491-492. 被引量:32
  • 3龚强,张士龙,方军,琚建军,曾甫清.URS-PL和ESWL治疗输尿管结石的有效性和安全性分析[J].临床泌尿外科杂志,2007,22(6):414-417. 被引量:13
  • 4吴阶平,顾方六,郭应禄,等.昊阶平泌尿外科学[M].济南:山东科学技术出版社,2004:1224-1225.
  • 5叶章群,邓耀良,董诚,等.泌尿系结石[M].2版.北京:人民卫生出版社,2010 : 630 - 631.
  • 6叶章群,邓耀良,董诚,等.泌尿系结石/第2版[M].北京:人民卫生出版社,2010,10:102-114.
  • 7Wimpissinger F, Turk C, Kheyfets O, et al. The silence of the stones: asymptomatic ureteral calculi[J]. J Urol, 2007,178:1341-1344.
  • 8Ryall RL. The future of stone research: rummaging in the attic, Randall's plaque, nanobacteria, and lessons from phylogeny [J]. Urol Res, 2008,36(2): 77-97.
  • 9Worcester EM, Coe FL. Calcium kidney stones [J]. N Engl J Med, 2010, 363(10): 954-963.
  • 10Frackowiak A, Skibinski P, Gawel W, et al. Synthesis of glycoside derivatives of hydroxyanthraquinone with ability to dissolve and inhibit formation of crystals of calcium oxalate. Potential compounds in kidney stone therapy[J]. European Journal of Medicinal Chemistry, 2010, 45(3): 1001-1007.

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