摘要
目的调查住院患者质子泵抑制剂(PPIs)的使用情况,为临床合理用药及制定管理措施提供参考。方法通过医院计算机信息管理系统,统计2011年1月—12月的住院总人次及药品销售总金额;使用PPIs人次及销售金额;PPIs针剂使用人次及销售金额;PPIs片剂使用人次及销售金额;各病区住院总人次及使用PPIs人次。然后随机抽取20个临床科室使用了PPIs的病历240份进行统计与分析。结果 36 741例住院患者中PPIs使用率34.86%,药占比为4.29%;使用率超过50%的科室有消化内科、急诊科、重症监护病房、肿瘤科、神经外科、呼吸内科和神经内科等;PPIs使用人次及销售金额以泮托拉唑肠溶片居首;不合理使用的病历数161份(67.08%,161/240),其中以超适应症用药最多(占80.74%,130/161)。结论住院患者中PPIs的使用情况存在不少不合理使用情况,严格按药品说明书用药,国家和医院制定PPIs使用指南或行政规定是规范PPIs使用的根本措施。
OBJECTIVE To investigate proton pump inhibitor （PPIs） use in inpatients and provide the references for clinical rational drug use and formulate the management measures. METHODS The hospital computer information management system was used to count the total number of hospitalization and the total amount of PPIs sales; the number of patient using PPIs and the amount of sales; the number of patient using PPIs for injections and the amount of sales; the number of patient using PPIs tablets and the amount of sales; the total number of patients in wards of the hospital and the use times of PPIs from January to December in 2011. Then 240 medical records had been extracted randomly from 20 departments and had been completed statistics and analysis. RESULTS In 36 741 records, the percent of patients was 34.86% using PPIs, the amount of sales of PPIs accounted for 4.29% of the total amount of drug sales. The use rate of more than 50% in that departments and they were gastroenterology, emergency, ICU, oncology, neurosurgery, respiratory medicine and neurology. The PPI of most use tmies and sales amount was pantoprazole enteric coated tablet. The medical record numbers of irrational PPIs use were 161（67.08%, 161/240）. In that irational use records, the most records were super-indications use（80.74%, 130/161）. CONCLUSION There have been many irrational PPIs use in hospitalized patients in our hospital. It is the fundamental measures that use PPIs should be strictly accordance with the instructions of PPIs, draw up the use PPIs guidelines of national unity, or administrative provisions for the hospitals.
出处
《中国现代应用药学》
CAS
CSCD
2014年第1期106-109,共4页
Chinese Journal of Modern Applied Pharmacy
基金
宜春市科技计划项目(JXYC2011KSB034)
关键词
质子泵抑制剂
住院患者
合理用药
分析
proton pump inhibitors
inpatients
rational drug use
analysis
