摘要
目的 探讨血浆血小板 α颗粒膜蛋白 (GMP- 1 4 0 )水平的变化在老年冠心病中的意义。方法 用放免法测定 2 4例老年冠心病和 2 0例正常老年人的血浆 GMP- 1 4 0水平 ,同时测定末梢血小板 (Plt)计数 ,血浆凝血酶原时间 (PT)及心肌酶学。结果 急性心肌梗死 (AMI)和不稳定性心绞痛 (UAP)患者血浆 GMP- 1 4 0明显增高 ,GMP- 1 4 0与心肌酶学及心肌梗死和心绞痛缺血面积均呈正相关。结论 GMP- 1 4 0是 AMI和
Objective To discuss the significance of plasma level changes GMP 40 in old patients with coronary atherosclerotic heart disease(CAHO).Methods The plasma level of GMP 40 was measured among CAHD group( n =24) and control group( n =20) using radioimmunoassay.Platelet(PLT),plasma prothrombin time(PT) and myocardial enzymes were measured too.Results The plasma level of GMP 140 was much higher in the acute myocardial infarction(AMI) and unlimited angina pectoris(UAP) group than that in the control group( P <0 05).There was a correlation between plasma level of GMP 140 and the change of myocardial enzymes.as well as the ischemic area of AMI and UAP.Conclusions Plasma level of GMP 140 might be a important indicator to observe the change of disease and the prognostic of disease.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
2001年第1期20-21,共2页
Chinese Journal of Gerontology