摘要
目的探讨了脑梗死患者治疗前后血清GM-CSF和血小板α-颗粒膜蛋白(PGMP)水平的变化及意义。方法应用放射免疫分析对36例脑梗死患者进行了血清GM-CSF和PGMP水平测定,并以30例正常健康人作比较。结果在治疗前血清GM-CSF和PGMP水平均非常显著地高于正常人组(P<0.01),经治疗后6个月与正常人比较仍有显著差异(P<0.05)。结论脑梗死的发生、发展与血清GM-CSF和PGMP水平密切相关。
Objective To investigate the changes of serum GM - CSF and PGMP levels after treatment in patients with cerebral infarction. Methods Serum GM - CSF and PGMP eontents were measured with RIA in 36 patients with cerebral infarction both before and after treatment as well as in 30 controls. Results Before treatment, the serum GM - CSF and PGMP levels in the patients were significantly higher than those in the controls （ P 〈 0.01 ）. After 6 months＇ treatment, the levels （ though dropped markedly ）, remained significantly higher （P 〈 0. 05）. Conclusion Serum GM - CSF and PGMP levels might be of prognostic value in patients with cerebral infarction.
出处
《放射免疫学杂志》
CAS
2006年第6期475-476,共2页
Journal of Radioimmanology
关键词
脑梗死
粒细胞巨噬细胞-集落刺激因子
血小板Α-颗粒膜蛋白
cerebral infarction, granulocyte -macrophage colony stimulating factor （GM -CSF）, platelet granular membrance protein （PGMP）
