摘要
目的 探讨脑出血 (CH)病人不同时期血清中一氧化氮 (NO)含量变化的临床意义。方法 采用Green改良法检测 38例不同时期CH病人血清中NO含量 ,并配有 30例正常对照组。结果 CH不同时期血清中NO含量的均数低于对照组 ,7d组NO含量最低 ;而 2 4h组NO含量明显高于其它组及对照组。脑出血的出血量与NO含量呈负相关。不同出血部位的NO含量从高到低依次是 :小脑、丘脑、壳核和脑叶。结论 脑出血病人的NO含量的动态变化说明 :NO是脑出血后病理生理变化的重要因素之一。
Objective To study the clinical significance of changes in serum nitric oxide content in different periods of cerebral hemorrhage.Methods Modified Green's method was used to measure serum NO content in 38 cerebral hemorrhage patients and 30 subjects were tested as the normal control group.Results The average serum concentrations of NO in different periods of cerebral hemorrhage were lower than those in the control group,while the serum NO concentration in 24 hour group was significantly higher than that in other groups and control group.The degree of cerebral hemorrhage was negatively correlated with NO content in serum and the NO contents were different in various regions of cerebral hemorrhage.Conclusion NO is involved in the pathophysiology of cerebral hemorrhage.This provides theoretical basis for managing cerebral hemorrhage in clinical practice.
出处
《中华老年心脑血管病杂志》
CAS
2001年第1期31-33,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
