摘要
目的 :探讨疏血通注射液治疗冠心病的疗效及作用机制。方法 :40例冠心病患者随机分为 2组 ,治疗组 2 0例在基础治疗的同时给予疏血通注射液静滴 ,对照组进行基础治疗 ,治疗前后比较 2组患者血浆内皮素(ET)、血栓素 B2 (TXB2 )、6酮前列腺素 F1α(6 keto PGF1α)及血液流变性的变化。结果 :治疗组治疗后临床症状好转 ,ET、TXB2 下降 ,6 keto PGF1α升高 ,血液流变学指标改善。结论 :疏血通注射液可扩张血管 ,增加血流量 ,抗凝及改善血液流变性 ,是治疗冠心病的有效药物。
Objective:To investigate the curative effects and mechanism of Shuxuetong injection (疏血通注射液) on treating coronary heart disease(CHD).Methods:The treated group ( n =20) based on conventional therapy was treated with Shuxuetong injection infused intravenously,meanwhile the control group treated with conventional therapy only.Before and after therapy the changes in concentrations of plasma endothelin(ET),thromboxin B 2(TXB 2),6ketoprostaglandin F 1α (6ketoPGF 1α ) and blood rheology between two groups were compared.Results:After therapy the clinical symptoms were convalescent,the ET and TXB 2 reduced,the 6ketoPGF 1α increased,and the parameters of blood rheology improved.Conclusions:Shuxuetong injection is able to dilate vessels,increase blood flow volume,anticoagulate,and improve blood rheology so that it is effective drug to treat CHD.
出处
《中国中西医结合急救杂志》
CAS
2001年第1期25-26,共2页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
关键词
冠心病
疏血通注射液
内皮素
血液流变性
医药疗
coronary heart disease
Shuxuetong injection
endothelin
thromboxin B 2
6ketoprostaglandin F 1α
blood rheologD
