摘要
目的观察木立芦荟外敷对华蟾素静脉滴注后静脉炎的防治作用。方法将90例采用华蟾素静脉滴注治疗的肿瘤患者随机分为治疗A组(予木立芦荟外敷)、治疗B组(予金黄散外敷)与对照组(予0.9%NaCl溶液外涂),每组30例。各组疗程均为3周,观察治疗第7天、第14天与治疗后静脉炎发病率及症状积分。结果治疗第7天、第14天与治疗后组内比较,各组静脉炎发生率、症状积分差异均有统计学意义(P<0.05)。组间治疗第7天比较,治疗B组与治疗A组、对照组静脉炎发生率、症状积分差异有统计学意义(P<0.05),而治疗A组与对照组静脉炎发生率、症状积分差异无统计学意义(P>0.05);组间治疗第14天、治疗后分别比较,治疗A组、治疗B组与对照组静脉炎发生率、症状积分差异有统计学意义(P<0.05),而治疗A组与治疗B组静脉炎发生率、症状积分差异无统计学意义(P>0.05)。结论木立芦荟与金黄散外敷防治华蟾素静脉滴注后局部静脉炎均有一定疗效,但木立芦荟起效较慢,二者远期防治效果相当。
Objective To observe the clinical efficacy of external application of Aloe in preventing and treating phlebitis after injection of Cinobufacini. Methods Ninety cases with phlebitis after injected Cinobufacini were randomized into three groups: treatment A group in which 30 cases were treated with Aloe, treatment B group in which 30 cases were treated with "Jinhuang Powder" and control group in which 30 cases were treated with NS, with the course of 3 weeks. We observed the morbidity and symptom score at the 7th and 14th day after treatment. Results At the 7th and 14th day after treatment, there were significant differences in morbidity and symptom score in each group (P 〈 0.05 ). At the 7th day after treatment, there were significant differences in morbidity and symptom score between B group and the other two groups (P 〈 0.05 ), without significant difference between A group and control group (P 〉 0.05 ) ; At the 14th day after treatment, there were significant differences in morbidity and symptom score between treatment groups and control group ( P 〈 0.05 ), without significant difference between A group and B group ( P 〉 0.05 ). Conclusion External application of Aloe and "Jinhuang Powder" has certain effect on phlebitis after injection of Cinobufacini. While Aloe showed slow action. From the long-term effect, Aloe showed similar effect to "Jinhuang Powder".
出处
《上海中医药杂志》
2014年第2期45-47,共3页
Shanghai Journal of Traditional Chinese Medicine
基金
上海中医药大学校级课题(200991)
关键词
静脉炎
木立芦荟
华蟾素注射液
防治作用
phlebitis
Aloe
Cinobufacini Injection
preventive and therapeutic effect