摘要
超声聚焦 (HIFU)由换能器发射的超声波组成 ,该高强度聚焦超声波主要通过热效应及其他机理引起组织损伤。用HIFU处理过的肿瘤组织表现为热细胞毒坏死和纤维化 ,导致肿瘤生长抑制。因此 ,HIFU是以高新技术为基础 ,微创治疗肿瘤的手段之一 ,且无放射毒副作用。目前已有多种肿瘤用HIFU治疗的研究报道 ,如 :前列腺癌、肝癌、肾肿瘤、膀胱癌、乳腺癌和脑肿瘤等 ,其中一些肿瘤在临床和实验研究中获得了有效控制肿瘤生长的疗效 ,尤其是前列腺癌。虽然HIFU作为一种治疗肿瘤的微创外科技术由于其卫生经济、病人易接受、死亡率低而引起了人们的极大关注 。
High_intensity focused ultrasound(HIFU)consists of focused ultrasound waves emitted from a transducer that are potential of inducing tissue damage.By means of this thermal effect and other mechanisms,HIFU treated tumor tissues showed direct thermal cytotoxic necrosis and fibrosis,which lead to inhibition of tumor growth.Therefore,HIFU was thought to be a new sophisticated high_technology based,minimally invasive treatment option for some cancers,which allows radiation_free treatment.Until now there are many kinds of tumors,such as tumors of prostate,liver,kidney,bladder,breast and brain,especially the prostate cancers treated with HIFU.Some of which showed effective tumor growth controlled clinically and experimentally.Although HIFU as one of the minimally invasive surgical techniques for cancer treatment is of great interest today,particularly for reasons of health economics,patient acceptability and reduced mortality.The feasibility and mechanisms of HIFU for treatment of human cancers need to be confirmed further.
出处
《中国肿瘤》
CAS
2001年第2期109-111,共3页
China Cancer
关键词
超声聚焦
肿瘤
治疗
前列腺肿瘤
high-intensity focused ultrasound
neoplasms
treatment
prostate neoplasms
