摘要
目的 :对25例扁桃体原发性恶性肿瘤的临床病理特征 ,进行分析研究。方法 :收集25例经临床病理证实的扁桃体原发性恶性肿瘤患者的临床资料 ,复习有关病理组织常规切片 ,部分病例标本进行免疫组织化学染色、显微镜观察分析。结果 :鳞状细胞癌7例 ,恶性弥漫性非霍奇金淋巴瘤17例 ,血管肉瘤1例 ;淋巴瘤白细胞共同抗原(CD45)均为阳性表达 ,大多为B细胞来源 ,而细胞角蛋白(CK)均为阴性 ;鳞癌CK均为阳性表达 ,而CD45和波形蛋白(Vimentin)均为阴性 ;血管肉瘤表达F8和Vimentin。结论 :扁桃体原发性恶性肿瘤以弥漫性非霍奇金淋巴瘤最为常见 ,其次是鳞癌 ,最后确诊要依靠病理形态学及免疫组织化学来证实 。
Objective:To analyze the clinicopathogical characteristics in 25 cases of primary malignant tumor of the tonsil.Methods:The clinical information of 25 cases of primary malignant tumor of the tonsil in our hospital were collected and analyzed by checking their pathological slices or by immuno histochemical method.Results:Pathological types:7 cases squamous cell carcinoma (SCC),17 cases malignant non Hodgkin's lymphoma,1 case angio sarcoma.Immunological types:expression of lymphoma leuko common antigen CD45 was positive,deriving from B cell,while cell keratin(CK) was negative.Expression of CK from SCC was positive,while CD45 and vimentin were negative,F8 and vimentin were positive in angiosarcoma.Conclusion:Most of the primary tonsil malignant tumor is non Hodgkin's lymphoma,the next is SCC.The key diagnosis depends on the pathological and immunohistochemical test.
出处
《四川肿瘤防治》
2001年第1期23-24,共2页
Sichuan Journal of Cancer Control
关键词
扁桃体
恶性肿瘤
临床表现
Tonsil
Malignant neoplasm
Clinical symptom
