摘要
目的 :研究局部应用甲状腺素 (ThyroidHormoneT3)对周围神经再生的作用。方法 :硅胶管套接大鼠坐骨神经 ,将T3、生理盐水分别加入硅胶管中。术后 4周和 12周 ,运用坐骨神经功能指数 (SFI)、光镜、电镜等方法分别从功能和形态方面测定各项指标。结果 :T3组再生神经在功能和形态方面均优于生理盐水组。结论 :局部应用甲状腺素能有效地促进周围神经再生。
Objective:The effect of T 3 on local adminitration on peripheral nerve was studied.Methods:Sciatic nerve sectioned in rat was sutured into silicone chamber.T 3 or physiological saline was injected into the silicone chambers during nerve repair.4 weeks and 12 weeks later,functional and morphology recovery of nerve regeneration was observed by means of sciatic function index,light microscope and electron microscope.Results:T 3 group excelled physiological saline group in both functional and morphology recovery of regenerating nerve.Conclusions:the local administration of thyroid hormones can effectively promote the regeneration of peripheral nerve.
出处
《河南实用神经疾病杂志》
2001年第1期30-32,共3页
Henan Journal of Practical Nervous Diseases
