摘要
目的 探讨急性轮状病毒 (RV)腹泻患儿病毒血症的发生情况。方法 大便ELISA一步法证实为急性RV腹泻的不同年龄患儿 2 0 0例 ,RT -PCR法检测其血清中RV。结果 入院当日 14例血清RV阳性 ,不同年龄组间无显著差异 (χ2=1.96 ,P(0 .2 5 ) ,均伴有不同程度肠外器官损害表现和明显发热 ;腹泻停止后血中RV全部阴性 ,大便 73例阳性。结论 急性RV腹泻患儿可通过病毒血症引起肠外器官损害 。
S:Aim To explore the incidence of virusemia in childhood patients with acute rotavirus(RV) infectious diarrhea.Methods Reverse transcriptase polymerase chain reaction(RT-PCR) was applied to detect RV in serum from 200 infants and young children with acute diarrhea(RV positive in stool confirmed by ELISA ).Results (1)14 cases were serum RV positive at the first day of hospitalization, accompanied by obvious fever and symptoms of extra-intestinal organs damage. There was not significant difference between various age groups (P>0.25).(2)73 patients were RV positive at the moment diarrhea disappeared.Conclusion RV virusemia may cause damage of extra-intestinal organs. The asymptomatic RV carrier after diarrhea disappearance could be one important source of infection.
出处
《中国人兽共患病杂志》
CSCD
北大核心
2001年第1期31-32,共2页
Chinese Journal of Zoonoses
