摘要
目的:探讨临床治疗直肠癌的有效术式。方法:收治直肠癌患者73例,根据术式将上述患者分为研究组41例与对照组32例;研究组接受保肛术治疗,对照组接受Miles术治疗。治疗结束后对患者进行为期3年的随访。结果:①两组手术时间相比差异无统计学意义(P>0.05),研究组术中出血量、术后肛门排气时间、术后留置导尿管时间、住院总时间显著低于对照组,两组比较差异有统计学意义(P<0.05)。②观察组术后Karnofsky功能状态评分显著高于对照组,两组比较差异有统计学意义(P<0.05)。③两组术后局部复发率、远处转移率、1年生存率、3年生存率相比差异无统计学意义(P>0.05)。结论:保肛术与Miles术治疗直肠癌的远期疗效相当,但是保肛术具有术后恢复快、生存质量高等优点,因此保肛术是临床治疗直肠癌的有效术式。
Objective:To explore the effec-tive operation for clinical treatment of rectal cancer.Method:73 cases of Patients with rec-tal cancer are cured in our hospital from January 2006 to December 2009,The above patients are divided into 41 cases of the re-search group and 32 cases of the control group;Patients with the team accept anal sphincter preservation,The control group pa-tients accept the Miles operation.We will follow-up them after the treatment for three years.Results: ①There was no statistically significant difference to compare with two groups of patients with operation time(P〈 0.05),amount of bleeding,Postoperative anal exhaust time, Postoperative urethral cathe-ter time and the total time in hospital in the research group are significantly lower than the control group during operation,there was statistically significant difference to com- pare with two groups(P〈 0.05). ②The re-search group is significantly higher than the control group on Karnofsky performance sta- tus score after operation,there was statisti-cally significant difference to compare with two groups(P 〈 0.05).To compare two groups of patients with postoperative local recur-rence and distant metastasis rate,survival rate 1 year,3 year survival rate,there was no statistically significant difference(P〉0.05). Conclusion:anal sphincter preservation and the Miles operation have the quite long-term curative effect,But,anal sphincter preservation have advantages of fast recov-ery,high quality of life,therefore,anal sphinc- ter preservation Is effective in the clinical treatment of rectal cancer surgery.
关键词
保肛术
MILES术
直肠癌
Anal sphincter preservation
Miles operation
Rectal cancer