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经阴道彩色多普勒对多囊卵巢综合征治疗前后子宫卵巢动脉血流动力学的研究 被引量:13

Assessment on Hemodynamics of the Ovarian and Uterine Arteries in the Patients with Polycytic Ovarian Syndrome by Transvaginal Color Doppler Flow Image before and after Treatment
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摘要 经阴道彩色多普勒(TV-CDFI)观察多囊卵巢综合征(PCOS)患者药物治疗前后子宫、卵巢动脉的血流变化,旨在探讨TV-CDFI在不孕症及生殖内分泌领域的应用价值。对15例PCOS患者治疗前后采用TV-CDFI,对子宫卵巢动脉进行检测。结果表明:PCOS患者治疗前子宫、卵巢动脉在月经的不同时期收缩期峰值速度(PSV)与阻力指数(RI)均无显著性差异(P<0.05)。经hMG治疗后,子宫、卵巢动脉恢复了周期性变化,且子宫内膜增厚。优势侧卵巢动脉PSV、RI均显著低于对侧(P<0.05)。结果提示:通过检测子宫、卵巢动脉血流阻力的动态变化,不仅可判断药物对PCOS患者的疗效,而且子宫动脉血流阻力亦可作为子宫内膜接受性的良好指标,有助于预测妊娠。 The changes of ovarian and uterine blood flow in the patients with polycystic ovarian syndrome (PCOS) by transvaginal color Deppler flow image (TV-CDFI) before and after medicinal treatment were as- sessed to investigate the values of TV-CDFI in the areas of in fertility and reproductive endocrine. The uterine and ovarian arteries in the 15 patients with PCOS before and after treatment were monitored by TV-CDFI. The results showed that there was no significantly statistical difference in either peak systolic velocity (PSV) or resistance index (RI) of the uterine and ovarian flow in the patients with PCOS before treatment during the dif- ferent periods of menstruation (P < 0. 05 ). After the treatment with human menopausal gonadotropine (hMG), the uterine and ovarian flow recovered cyclic changes and endometrium was thicker than before. The PSV and RI in predominantly lateral ovarian artery were significantly lower than those of the contralateral ovar- ian artery (P<0. 05). Study on the changes of flow resistance of the uterine and ovarian arteries could assess the effect of medicines in the patients with PCOS. RI of uterine artery flow was a good indicator of endometrial receptivity and was helpful to predict the possibility of pregnancy.
出处 《同济医科大学学报》 CSCD 2000年第6期584-587,共4页 Acta Universitatis Medicinae Tongji
关键词 经阴道彩色多普勒超声 多囊卵巢综合征 治疗 transvaginal color Doppler flow image polycystic ovarian syndrome uterine and ovarian arteries resistance index
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  • 1[1]Aleem F A. Predanic M. Transvaginal Color Doppler determinotion of the varian and uterine blood flow characteristic in polycystic ovary disease. Fertil Steril, 1996,65:510
  • 2[2]Hoch D L, Bohrer M K, Ananth C V. Sonographic assessment of endometrial pattern and thickness in patients treated with clomiphene citrate human menopausal gonadotropins and intrauterine insemination. Fertil Steril, 1997,68:242
  • 3[3]Cacciatore B, Simberg N, Tiitinen A. Evidence of inerplay between plasma endothelin-1 and 17 β-estradiol in regulation of uterine blood flow and endometrial growth in intertile women. Fertil Steril, 1997,67:883
  • 4[4]Zaidi J, Kyei-Mensch A, Pittrof R. Assessment of uterine artery blood flow on the olay of human chorionic gonadotropin administration by transvaginal color Doppler ultrasound in an in vitro fertilization program. Fertil Steril, 1996,65:377

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