摘要
观察碱性成纤维细胞生长因子（ｂＦＧＦ）对糖尿病患者烧伤难愈创面修复的影响。２２例、２７个糖尿病烧伤超过６周未愈合的创面，经清创后按１５０ｕ／ｃｍ２创面应用外源性ｂＦＧＦ，每日１～２次，对照治疗前、后创面愈合情况。结果显示：２７个慢性难愈合创面在应用ｂＦＧＦ后，４周内全部愈合，总有效率达１００％。提示：ｂＦＧＦ能明显改善糖尿病烧伤难愈创面的修复环境，加速创面愈合。
The effects of basic fibroblast growth factor (bFGF) on repairing cutaneous burn wounds in the diabetes patients were investigated. Twenty-seven wounds of 22 diabetes patients whose wound hadn't been re- paired over 6 weeks were locally treated with bFGF in a dosage of 150 U/cm2 for each wounds one or two times a day. The healing time of the wound was used to evaluate of treatment results. The results showed that all cu- taneous burn wounds cured within 4 weeks after treatment with the effective rate being 100%. The results in- dicated that bFGF can be used as a promoter to accelerate the healing of cutaneous burn wounds in the diabetes patients in clinical practice.
出处
《同济医科大学学报》
CSCD
2000年第6期545-546,共2页
Acta Universitatis Medicinae Tongji
关键词
糖尿病
烧伤
碱性成纤维细胞生长因子
创面修复
diabetes mellitus
burn
cutaneous chronic wounds
basic fibroblast growth factor
repair
