摘要
目的选择一种药物治疗宫外孕的最佳方法 ,减轻患者手术创伤 ,保护输卵管的功能 ,保留生殖能力。方法将 5 9例患者随机分成三组 :A组口服米非司酮 (RU486 )治疗 2 0例 ;B组静脉推注氨甲喋呤 (MTX)治疗 2 0例 ;C组RU486与MTX联合用药治疗 19例。结果A组治愈率 75 % ,HCG转阴时间 2 1.13± 9.4天 ,无药物副反应发生 ;B组治愈率 85 % ,HCG转阴时间 2 0 .42± 7.36天 ,胃肠道反应发生率 2 0 % ,表现轻度恶心、呕吐 ,口腔溃疡发生率10 % ;C组治愈率 97 4% ,HCG转阴时间 16 .11± 7.0 2天 ,无药物毒副反应。结论联合用药能减少用药剂量 ,缩短疗程 ,减少毒副反应 ,具有安全。
Objective To select a optimum ectopic pregnancy treating method by medicine to reduce operational wound, protect the function of oviduct and preserve reproducing ability. Method 59 cases of patients were randomly divided into three group and treated by different medcine;group A, 20 cases intake Mifepriston, group B, 20 cases has intravenous injection of Methotrexate;group C, 19 cases were given both Mifepriston and Methotrexate.Results The rate of cure in group A was 75%, and the time for HGG negative was 21 13±9.4 days, no side effect was found. The rate of cure in group B was 85%, and the time for HGG negative was 20.42±7 36 days. The incidence of gastro intestine reaction was 20%, mild nausea and vomiting was found, incidence of oral cavity uncle was 10%.The rate of cure for group C was 97.1%, and the time for HGG negative was 16.11±7.02 days, no side effect was found.Conclusion Combined medicine treatment can reduce dosage, shorten recovery course and reduce side effect, and has the advantage of safe and affirmed treating effect.
出处
《护士进修杂志》
北大核心
2000年第12期891-892,共2页
Journal of Nurses Training
关键词
宫外孕
米非司酮
氨甲喋呤
护理
药物疗法
Ectopic pregnancy Mifepriston Methotrexate Observation and nursing.
