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卒中后抑郁障碍:机制、诊断与治疗 被引量:33

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摘要 抑郁是较常见的卒中后神经精神症状之一。在卒中发病后最初3个月内卒中后抑郁障碍(post-strokedepression,PSD)的累计患病率是27.3%[1],在最初1年内PSD的累计发生率为41.8%[2]。近半数PSD患者随着时间的延长仃订康复,然而部分患者几个月后或2年内将成为重度抑郁患者,还有…部分患者抑郁症状变化不定[3]。
出处 《中国卒中杂志》 2014年第1期5-8,共4页 Chinese Journal of Stroke
基金 江苏省科技创新与成果转化(生命健康科技)专项资金(BL2012025)
关键词 卒中 抑郁 治疗
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参考文献20

  • 1Zhang T,Wang C,Liu L. A prospective cohort study of the incidence and determinants of post-stroke depression among the mainland Chinese patients[J].{H}Neurological Research,2010.347-352.
  • 2Zhang N,Wang CX,Wang AX. Time course of depression and one-year prognosis of patients with stroke in China's Mainland[J].CNS Neurosci Ther,2012.475-481.
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  • 7Yang L,Zhang Z,Sun D. The serum interleukin-18 is a potential marker for development of post-stroke depression[J].{H}Neurological Research,2010.340-346.
  • 8Shi Y,You J,Yuan Y. Plasma BDNF and tPA are associated with late-onset geriatric depression[J].{H}Psychiatry and Clinical Neurosciences,2010.249-254.
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  • 10Blaveri E,Kelly F,Mallei A. Expression proifling of a genetic animal model of depression reveals novel molecular pathways underlying depressive-like behaviours[J].PLoS One,2010.e12596.

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