摘要
目的 通过Meta分析比较正电子计算机体层扫描（PET-CT）与核磁共振成像（MRI）对国人鼻咽癌转移的诊断价值.方法 计算机检索万方数据库、中国学术期刊网全文数据库（CNKI）和维普数据库从1989年1月～2013年5月收录的PET-CT与MRI诊断国人鼻咽癌转移的临床诊断试验,并对纳入文献采用Meta-Disc软件进行Meta分析.结果 最终纳入文献5篇,共636例患者.Meta分析结果显示,PET-CT诊断鼻咽癌转移95％CI的SEN、SPE分别为35％（33％～37％）、94％（91％～96％）,SROC曲线下面积（AUC）为0.7247,SE（AUC）为0.2399;而MRI诊断鼻咽癌转移95％CI的SEN、SPE分别为35％（33％～37％）、84％（80％～87％）,SROC曲线下面积（AUC）为0.7654,SE（AUC）为0.1154.以上结果表明与MRI相比,PET-CT在国人鼻咽癌转移诊断中具有较低的误诊率,但诊断价值稍低.结论 根据现有的诊断试验,PET-CT和MRI均是诊断国人鼻咽癌转移的有效技术手段.在误诊率方面,PET-CT优于MRI;但诊断价值稍低.因此,两者紧密结合才能使鼻咽癌转移的检出率明显增高.
Objective To compare the values of positron emission tomography-computer tomography （PET-CT） and magnetic resonance imaging （MRI） in the diagnosis of nasopharyngeal carcinoma metastasis of Chinese patients by a meta-analysis.Methods By computer retrieval of Wanfang database,China academic journal full-text database （CNKI） and VIP database from January 1989 to May 2013,they were brought into clinical diagnostic tests about PET-CT and MRI in diagnosis of metastasis of nasopharyngeal carcinoma,and the Meta-Disc was used to a meta-analysis.Results Five tests about a total of 636 patients were used into Meta-analysis.According to the results of PET-CT in the diagnosis of nasopharyngeal carcinoma metastasis,95%CI of sensitivity （SEN）,specificity （SPE） was 35% （33%-37%）,94% （91%-96%）,SROC area under curve （A UC） was 0.7247,SE（A UC） of 0.2399; and MRI diagnosis of nasopharyngeal carcinoma metastasis 95%CI of SEN,the SPE was 35%（33%-37%）,84%（80%-87%）,SROC area under curve （A UC） was 0.7654,the SE （A UC） of 0.1154.The above results show that compared with MRI,PET-CT in Chinese transfer diagnosis of nasopharyngeal carcinoma has lower misdiagnosis rate,but slightly low diagnostic value.Conclusion According to the existing diagnostic tests,PET-CT and MRI in diagnosis of nationality are both effective technical means of nasopharyngeal carcinoma metastasis.PET-CT is superior to MRI in misdiagnosis rate,but slightly low diagnostic value.Thus,combine those two methods can significantly improve the detection rate of nasopharyngeal carcinoma metastasis.
出处
《中国医药导报》
CAS
2014年第2期81-84,共4页
China Medical Herald
