期刊文献+

腹腔镜全子宫切除术对患者氧化应激水平的影响 被引量:4

Effects of laparoscopic total hysterectomy on systemic oxidative stress
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摘要 目的探讨腹腔镜全子宫切除术(LTH)和开腹全子宫切除术(TAH)对患者机体氧化应激水平的影响。方法选择2010年3月至2012年3月在我院进行LTH和TAH的手术患者各38例。分别于手术前、手术结束即刻及手术后24 h检测两组患者血中丙二醛(MDA)、超氧化物歧化酶(SOD)及谷胱甘肽过氧化物酶(GSH-PX)的水平并进行比较分析。结果与术前相比,两组患者手术结束即刻的MDA水平均增高,但LTH组增高较明显;术后24 h LTH组恢复至术前水平,而TAH组继续增高,差异具有统计学意义(P<0.05)。与术前相比,手术结束时两组患者血浆中SOD和GSH-PX活性均有所下降,但LTH组降低更明显;术后24 h LTH组中SOD和GSH-PX活性恢复至术前水平,而TAH组继续降低,差异具有统计学意义。两组相比,LTH组术后24 h MDA水平降低,SOD和GSH-PX的活性增高(P<0.05)。结论腹腔镜全子宫切除手术中由于CO2气腹等原因导致机体产生氧化应激,但术后恢复速度比开腹子宫切除术快。 Objective To investigate the effects of laparoscopic total hysterectomy on systemic oxidative stress. Methods Each 38 patients who underwent laparoscopic total hysterectomy (LTH) and total abdominal hyster- ectomy (TAH) respectively from March 2010 to March 2012 were enrolled in this study. Plasma malondialdehyde
作者 刘芳 符伟
出处 《海南医学》 CAS 2014年第1期32-34,共3页 Hainan Medical Journal
关键词 腹腔镜全子宫切除术 开腹全子宫切除术 CO2气腹 氧化应激 Laparoscopic total hysterectomy (LH) Total abdominal hysterectomy(TAH) CO2 pneumoperito-neum Oxidative stress
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参考文献8

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二级参考文献25

  • 1张广亮,刘国炳,黄琦丽,邢福祺.腹腔镜与开腹子宫肌瘤剜除术氧化应激状态的比较[J].第一军医大学学报,2004,24(8):907-909. 被引量:7
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